Avancerad sökning

Visar resultat 1 - 5 av 25 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Mercury-induced autoimmunity : Genetics and immunoregulation

   Författare :Monika Hansson; Manuchehr Abedi-Valugerdi; Marita Troye-Blomberg; Lucette Pelletier; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mercury; autoimmunity; collagen-induced arthritis; Th1 Th2; silver; tight-skin 1 mice; Immunology; Immunologi;

   Sammanfattning : The existence of immune self-tolerance allows the immune system to mount responses against infectious agents, but not against self-molecular constitutes. Although self-tolerance is a robust phenomenon, in some individuals as well as in experimental models, the self-tolerance breaks down and as a result, a self-destructive autoimmune disease emerges. LÄS MER

3. 2. Natural killer T (NKT) lymphocytes regulate of intestinal tumor immunity

   Författare :Ying Wang; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NKT lymphocyte; intestinal tumor; CD1d; colrectal cancer; immunoregulation; α-gagactosylceramide;

   Sammanfattning : CD1d-restricted natural killer T (NKT) lymphocytes are known as potent early regulatory cells of immune responses, acting as a bridge between innate and adaptive immunity. While invariant NKT (iNKT) cells have a protective role in many tumor models, their ability to promote intestinal inflammation, known to enhance intestinal cancer, raised the question if they would be protective in intestinal tumor development. LÄS MER

4. 3. Cellular and genetic components in the development of IDDM in NOD mice

   Författare :Kristina Lejon; Dan Holmberg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-obese diabetic; IgVh gene utilisation; immunoregulation; programmed cell death; genetic linkage analysis; immunologi; Immunology;

   Sammanfattning : .... LÄS MER

5. 4. Investigation of immune cell-derived factors as potential biomarkers in patients with colorectal cancer

   Författare :Levar Shamoun; Dick Wågsäter; Jan Dimberg; Kalle Landerholm; Blanka Kolodziej; Richard Palmqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gene polymorphism; Colorectal cancer; Immunoregulation; Prognosis; Gene and protein expression; Survival; Zmynd15; Genpolymorfism; Kolorektal cancer; Immunreglering; Prognos; Gen- och proteinuttryck; Överlevnad; Zmynd15; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Medical Cell Biology; Medicinsk cellbiologi; Patologi; Pathology;

   Sammanfattning : Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer related death. It is a heterogeneous disease involving multiple molecular pathways that result in differing phenotypes. Individual variability in CRC susceptibility is influenced by genetic variation, such as single nucleotide polymorphisms (SNPs). LÄS MER

7. 5. C-reactive protein (CRP) and anti-CRP autoantibodies in systemic lupus erythematosus : a study on the occurrence and clinical implications of anti-CRP antibodies and CRP-mediated complement activation

   Författare :Christopher Sjöwall; Thomas Skogh; Johan Frostegård; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoantibodies; complement activation; C-reactive protein; cytokines; immune complex; immunoregulation; opsonization; systemic lupus erythematosus; Rheumatology; Reumatologi;

   Sammanfattning : Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by production of a wide range of autoantibodies, multiple organ involvement and by local formation or tissue deposition of immune complexes (ICs) in the inflamed organs. In contrast to most systemic inflammatory conditions, and despite raised levels of pro-inflammatory cytokines, SLE flares are rarely reflected by elevated C-reactive protein (CRP), an important acute-phase reactant in man with homologs in vertebrates and several invertebrates. LÄS MER