Sökning: "immunocytochemistry"

Visar resultat 21 - 25 av 89 avhandlingar innehållade ordet immunocytochemistry.

  1. 21. Ion transport in exocrine glands with reference to cystic fibrosis

    Författare :Ailing Zhang; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; ion transport; cystic fibrosis; submandibular gland; airway submucosal gland; X-ray microanalysis; cytosolic Ca2 concentration; immunocytochemistry; Cellbiologi; Cell biology; Cellbiologi; Human Anatomy; anatomi;

    Sammanfattning : Aspects of ion transport in rat submandibular gland acinar cells at the subcellular level, and the regulation of chloride secretion and calcium mobilization in cultured pig tracheal gland acinar cells were studied with reference to the disease cystic fibrosis.In adult rat submandibular gland acinar cells, both cholinergic and α-adrenergic stimulation induced efflux of K+ and of C1-, but the response was generally less with α-adrenergic stimulation. LÄS MER

  3. 22. Characterization of malignant pleural mesothelioma : possibilities for an individualized therapeutic arsenal

    Författare :Adam Szulkin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Less than 50% of malignant mesothelioma patients respond to standard chemotherapy treatment and there is a great need to identify these patients, and find their best treatment options. The aim of this thesis was to increase the understanding of drug sensitivity in malignant pleural mesothelioma. LÄS MER

  4. 23. Improving biomarker assessment in breast pathology

    Författare :Stephanie Robertson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The accuracy of prognostic and therapy-predictive biomarker assessment in breast tumours is crucial for management and therapy decision in patients with breast cancer. In this thesis, biomarkers used in clinical practice with emphasise on Ki67 and HER2 were studied using several methods including immunocytochemistry, in situ hybridisation, gene expression assays and digital image analysis, with the overall aim to improve routine biomarker evaluation and clarify the prognostic potential in early breast cancer. LÄS MER

  5. 24. Stem cell in-vitro strategies for the induction of sensory neurons for inner ear cell therapy

    Författare :Rouknuddin Qasim Ali; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The cochlea, a part of the auditory system, is a complex structure consisting of several different types of cells including hair cells and spiral ganglion neurons. In mammals, the regenerative potential of hair cells and spiral ganglion neurons is lost soon after the birth and damage to any of these cells causes sensorineural hearing loss. LÄS MER

  7. 25. Human muscle spindles : complex morphology and structural organisation

    Författare :Jing-Xia Liu; William K. Ovalle; Umeå universitet; []
    Nyckelord :human; muscle spindle; intrafusal fiber; aging; biceps brachii; deep muscles of the neck; MyHC; mATPase; SERCA; anatomi; Human Anatomy;

    Sammanfattning : Muscle spindles are skeletal muscle mechanoreceptors that mediate the stretch reflex and provide axial and limb position information to the central nervous system. They have been proposed to play a major role in the pathophysiology of muscle pain. LÄS MER