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Visar resultat 1 - 5 av 1599 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response

    Författare :Rada Ellegård; Marie Larsson; Jorma Hinkula; Johan D Söderholm; William Paxton; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

    Sammanfattning : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. LÄS MER

  3. 2. Immune response to allergens : a clinical and experimental study

    Författare :Lennart Nordvall; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. Fcγ Receptors in the Immune Response

    Författare :Teresita Díaz de Ståhl; Jan van de Winkel; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Fc Receptors; IgG Receptors; IgE Receptors; Immune regulation; In vivo animal models; Mouse; Rh prophylaxis; Rheumatoid arthritis; Transgenic knockout; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Circulating immune complexes play an important role in the modulation of antibody responses and in the pathogenesis of immune diseases. This thesis deals with the in vivo regulatory properties of antibodies and their specific Fc receptors. LÄS MER

  5. 4. On the Immune Regulation of Bone Response to Biomaterials

    Författare :Ricardo Trindade; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomaterial; Immune System; Osseointegration; Foreign body reaction; Immune modulation; Titanium; Copper; Polyether ether ketone; PEEK;

    Sammanfattning : Osseointegration is the biological basis for bone anchorage of oral implants, and revolu-tionized the replacement of lost teeth. It is also applied in bone anchored hearing aids and limb replacement in amputees. LÄS MER

  7. 5. The Immune Response to One-Lung Ventilation : Clinical and Experimental Studies

    Författare :Thomas Schilling; Göran Hedenstierna; Hans Hedenström; Thomas Hachenberg; Sven-Erik Ricksten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; Medical laboratory science; Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

    Sammanfattning : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. LÄS MER