Sökning: "immune mediators"

Visar resultat 16 - 20 av 210 avhandlingar innehållade orden immune mediators.

  1. 16. Biomarkers and mediators in systemic lupus erythematosus : IFNα versus the CRP response, and evaluation of suPAR and anti-dsDNA antibody assays

    Författare :Helena Enocsson; Jonas Wetterö; Thomas Skogh; Christopher Sjöwall; Søren Jacobsen; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease which may affect multiple organ systems. Interferon alpha (IFNα) and autoantibodies that form immune complexes with nuclear antigens (ANA) are hallmarks believed to drive the disease into a vicious circle of inflammation, tissue damage, autoantigen exposure and autoantibody production. LÄS MER

  3. 17. Innate immune response in human endothelial cells : characterization and regulation of E-selectin, ICAM-I and cytokine expression and the role of Staphylococcus aureus

    Författare :Jan Strindhall; Åsa Ljungh; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Endothelial cells located on the vessel walls play an important role in inflammation. In response to cytokines or other inflammatory mediators such as microorganisms, endothelial cells express cell adhesion molecules such as E-selectin and ICAM-1 that are involved in binding circulating leukocytes to the endothelium. LÄS MER

  4. 18. Brain Stem Involvement in Immune and Aversive Challenge

    Författare :Jakob Paues; Anders Blomqvist; Finn Hallböök; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipopolysaccharide; Lithium Chloride; anorexia; aversion; parabrachial; brain stem; melanocortin; CGRP; enkephalin; Neurobiology; Neurobiologi;

    Sammanfattning : Activation of the immune system by e.g. bacteria induces the acute-phase-response and sickness behaviour. The latter encompasses among other things fever, lethargy, anorexia and hyperalgesia. LÄS MER

  5. 19. Dysregulated mucosal immune responses in microscopic colitis patients

    Författare :Sezin Günaltay; Elisabeth Hultgren-Hörnquist; Olof Hultgren; Nils Nyhlin; Allan Mowat; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microscopic colitis; collagenous colitis; lymphocytic colitis; TLR; chemokine; chemokine receptor; IL-37; TCR; Immunologi; Immunology; Biomedicin; Biomedicine;

    Sammanfattning : Microscopic colitis (MC), comprising collagenous colitis (CC) and lymphocytic colitis (LC) is a common cause of chronic watery diarrhea. The diagnosis relies on typical histopathological changes observed upon microscopic examination. LÄS MER

  7. 20. Neutrophil granule proteins : modulators of the immune response

    Författare :Oliver Söhnlein; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Polymorphonuclear leukocytes (PMN) are multifunctional cells of the innate immune system which represent the advance guard in inflammatory reactions. Via the release of granule proteins the PMN communicates with the endothelium, monocytes, dendritic cells, and lymphocytes and is thereby critically involved in the fine tuning of the host defense system. LÄS MER