Sökning: "immune mediators"

Visar resultat 11 - 15 av 210 avhandlingar innehållade orden immune mediators.

  1. 11. Superantigens in group A streptococcus : gene diversity and humoral immune response

    Författare :Linda Maripuu; Mari Norgren; Susan Hollingshead; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Group A streptococcus; Streptococcus pyogenes; superantigen SAg ; SAg-gene profile; M-protein; emm-genotype; biomedicinsk laboratorievetenskap; biomedical laboratory science;

    Sammanfattning : Group A streptococcus (GAS) is a strictly human pathogen that causes infections ranging from asymptomatic carriage to the highly lethal streptococcal toxic shock syndrome (STSS). GAS are classified according to the sequence of the variable 5’ end of the emm-gene that encodes the surface associated M-protein. LÄS MER

  3. 12. Immune modulation by mesenchymal stem cells

    Författare :Ida Rasmusson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mesenchymal stem cells; T cells; cytotoxic T lymphocytes; cytokines; mixed lymphocyte culture; B cells; antibody production; stem cell transplantation; acute graft versus host disease;

    Sammanfattning : Mesenchymal stem cells (MSCs) were discovered as adherent cells in the bone marrow stroma that could form bone and stimulate hematopoiesis. Later, MSCs were shown to be hypoimmunogenic and to suppress proliferation of activated T cells. LÄS MER

  4. 13. Extracellular vesicles : mediators of immune modulation in the lung and as therapeutic vehicles

    Författare :Casper Ullsten-Wahlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Extracellular vesicles (EVs) are released from all cell types, and carry a wide setup of proteins, nucleic acids, lipids and other cargo. The overall aim of this thesis is to explore EV-based immune therapy, but also to find clues on mechanisms of the inflammatory disease sarcoidosis, and of lung cancer. LÄS MER

  5. 14. Role of classical pro- and anti-inflammatory mediators in ischemic stroke. Beyond neuroimmunomodulation

    Författare :Ana Inacio; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; interferon-β; inflammatory immune cells; galectin-3; experimental stroke; enriched environment; cytokines; Brain; macrophage migration inhibitory factor; neuroprotection; reactive astrocytes.;

    Sammanfattning : Stroke is a leading cause of death and long-term neurological deficits worldwide, and no effective treatment is available for the vast majority of the stroke patients. A rapid and persistent activation of multiple and dynamic inflammatory and immune cascades, in and outside the brain, occurs after stroke. LÄS MER

  7. 15. Immune evasion and dissemination of Toxoplasma gondii

    Författare :Henrik Lambert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Toxoplasma gondii is an obligate intracellular protozoan parasite which propagates in a complex life cycle where infection of Felidae family-members (Cats) results in sexual recombination whereas all other warm-blooded animals are intermediate hosts. Approximately one third of the human population is estimated to be chronically infected by this parasite. LÄS MER