Sökning: "immobilization of scFv"

Hittade 4 avhandlingar innehållade orden immobilization of scFv.

  1. 1. Tailoring of Antibody Arrays - Technical Advances Towards Global Proteome Analysis

    Författare :Linn Petersson; Institutionen för immunteknologi; []
    Nyckelord :antibody arrays; recombinant antibodies; scFv; miniaturization of arrays; immobilization of scFv; global proteome analysis; biomarker discovery;

    Sammanfattning : Abstract The number of cancer and autoimmune disease diagnoses increases in our society, which place high demands on the health care system. Being able to tailor treatments for each individual patient is called "Personalized medicine", and could revolutionize the care in the future. LÄS MER

  3. 2. Biosensing and Protein Array Design using Lipid Assemblies

    Författare :Charlotte Larsson; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; protein adsorption; protein arrays; lipid bilayer; SPR; scFv; lipid vesicle; DNA arrays; QCM-D;

    Sammanfattning : Biomolecular sensing often includes immobilization of biomolecules, e.g. DNA, antibodies etc., to solid supports, where they act as selective recognition elements. LÄS MER

  4. 3. Technological Advancements in Affinity Proteomics : From planar antibody microarrays towards a solution-based platform

    Författare :Mattias Brofelth; Institutionen för immunteknologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Affinity proteomics; Antibody microarrays; scFv; Biomarkers; MIAS;

    Sammanfattning : Abstract: Proteomics has the potential to deliver disease-associated biomarkers that could provide diagnostic, prognostic and predictive information to enable precision medicine. Affinity proteomics, most commonly based on antibodies and their ability to specifically capture target proteins, has emerged has a valuable tool in biomarker discovery. LÄS MER

  5. 4. Recombinant Antibodies – Tools for building proteomic platforms

    Författare :Anna Säll; Institutionen för immunteknologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibody development; recombinant scFv antibodies; phage display; affinity proteomics; mass spectrometry;

    Sammanfattning : This thesis, which is based on four original papers, covers different aspects of the evolvement and development of proteomic platforms and the construction of human synthetic antibody libraries for the isolation of antibody reagents has been very central. There is an accelerating need for technologies capable of providing proteomic analysis of high sensitivity with good accuracy and an overall broad coverage as well as for biomarker validation. LÄS MER