Sökning: "immature vessels"

Visar resultat 6 - 10 av 11 avhandlingar innehållade orden immature vessels.

  1. 6. Observations on morphology and function of cutaneous and subcutaneous sensory mechanoreceptors : an experimental study in mammals

    Författare :Birgit Stark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :mechanoreceptors; somatosensory organisation; blood-nerve barrier; Glucose transporter-1; nerve regeneration; TGF-ß family; neurotrophin receptors;

    Sammanfattning : Tactile sensory discrimination is dependent upon an intact system of peripheral mechanoreceptors, their nerve fibre afferents with cell bodies in the dorsal root ganglion and the dorsal column-medial lemniscal system which relays tactile information from the skin to the cortex. Injury to any part of the afferent pathways leads to compromised mechanoreceptive perception. LÄS MER

  3. 7. VEGFR-2 in Endothelial Differentiation and Vascular Organization

    Författare :Dan Edholm; Lena Claesson-Welsh; Xiujuan Li; Victoria Bautch; Uppsala universitet; []
    Nyckelord :Molecular medicine; Embryonic stem; VEGFR-2; Flk1; KDR; VEGF; vasculogenesis; angiogenesis; embryoid body; Molekylärmedicin;

    Sammanfattning : The cardiovascular system is the first functional organ to develop during embryogenesis. As the embryo reaches above a certain size, passive diffusion of gases and nutrients is no longer compatible with efficient growth. LÄS MER

  4. 8. Human innate lymphoid cell trafficking and function in vivo

    Författare :Arlisa Alisjahbana; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human organs and tissues, such as the lung, are composed of various spatially distinct anatomical compartments. Each compartment represents a different tissue environment within the organ, performs specific functions and in turn promotes the development, migration, and function of specific cell types. LÄS MER

  5. 9. Vascular development : from embryonic stem cells to arteries and veins

    Författare :Fredrik Lanner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A fundamental question in developmental biology is how a single fertilized egg cell and its progeny are programmed or instructed to form thousands of different cell types and how these are organized into a complex and functional organism. In this thesis I have explored how a specific subset of cells is formed - the vascular endothelial cells lining our blood vessels. LÄS MER

  7. 10. Transcriptional Regulation by Hypoxia-Inducible Factors in Tumor Cells

    Författare :Tobias Löfstedt; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Biomedicinska vetenskaper; Medicine human and vertebrates ; Medicin människa och djur ; Cytology; Biomedical sciences; MXI1; ID2; differentiation; HIF; hypoxia; transcription; cancer; neuroblastoma; Cytologi; onkologi;

    Sammanfattning : Cancer is a major cause of human morbidity and mortality, and the risk of developing cancer is about one in three life times. Neuroblastoma is the most common extra-cranial solid tumor among children and arises from early sympathetic nervous system (SNS) cells arrested in their development. LÄS MER