Sökning: "ifenprodil"

Hittade 3 avhandlingar innehållade ordet ifenprodil.

1. 1. Neurosteroids Induce Allosteric Effects on the NMDA Receptor : Nanomolar Concentrations of Neurosteroids Exert Non-Genomic Effects on the NMDA Receptor Complex

   Författare :Tobias Johansson; Fred Nyberg; Pierre Le Grevès; Elisabeth Hansson; Uppsala universitet; []
   Nyckelord :Pharmaceutical pharmacology; Pharmacology; neurosteroids; NMDA receptor; NR2B subunit; ifenprodil; sigma receptor; anabolic androgenic steroids; allosteric modulation; non-genomic; Farmaceutisk farmakologi;

   Sammanfattning : The neurosteroids constitute a group of powerful hormones synthesized and acting in the central nervous system. They participate in a number of important central processes, such as memory and learning, mood and neuroprotection. LÄS MER

3. 2. Central nervous modulation of pain - a clinical and experimental study

   Författare :Christopher Lundborg; Göteborgs universitet; []
   Nyckelord :pain; head and neck; cisterna magna; baroreflex; noradrenaline; GDNF; co-cultured astrocytes; naloxon; osteoarthritis; calcium;

   Sammanfattning : This series of studies addresses several conceptual issues in modern pain therapy related to the contemporary understanding of mechanisms and modulators involved in the pain sensation. Novel invasive therapy for severe pain, neurogenic interactions, humoral regulators and cellular responses were studied. LÄS MER

4. 3. Chemical and stimulus-induced NMDA-dependent plasticity and the possible involved mechanisms

   Författare :Rui Li; Göteborgs universitet; []
   Nyckelord :synaptic plasticity; hippocampus; LTP; LTD; AMPA; NMDA; NR2A; NR2B;

   Sammanfattning : Long-term potentiation (LTP) and long-term depression (LTD) are considered as the most important forms of synaptic plasticity involved in learning and memory. The traditional way to induce LTP and LTD is by electric stimulation leading to activation of NMDA-R. LÄS MER