Sökning: "identification frame"

Visar resultat 16 - 20 av 63 avhandlingar innehållade orden identification frame.

1. 16. Identification, cloning and characterization of the p53 induced gene human Wig-1

   Författare :Fredrik Hellborg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The tumor suppressor p53 is a transcription factor that responds to various kinds of cellular stress. In respons to the sensed stress it is able to induces cell cycle arrest and apoptosis. In order to achieve these effects it transactivates target genes. LÄS MER

3. 17. Identification of the common eliminated region (CER1) by the microcell hybrid based 'elimination test'

   Författare :Ying Yang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Elimination test; common eliminated region 1 CER1 ; 3p21.3; microcell hybrids; tumor suppressor gene; LF lactoferrin ; LIMD1 LIM-domain containing gene 1 ; sequencing; MMCT microcell mediated chromosome transfer ; real time PM methylation;

   Sammanfattning : The aim of elimination test (Et) is to identify tumor antagonizing genes from chromosome regions that are regularly deleted in microcell hybrid (MCH) derived tumors through serial SCID mice passages. Et so far was focused on the short arm of human chromosome 3 (chr 3) due to its frequent deletions in 21 tumor types including renal cell carcinoma (RCC), small cell lung carcinoma (SCLC) and breast cancer (BRC). LÄS MER

4. 18. Dynamic Power System Load -Estimation of Parameters from Operational Data

   Författare :Ines Romero; Industriell elektroteknik och automation; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; control engineering; robotics; Automation; large disturbances; Load modeling; normal operation; voltage stability; dynamic load models; modeling and identification; normalization in reactive load models; Elektronik och elektroteknik; Electronics and Electrical technology; Automatiska system; robotteknik; reglerteknik; Electrical engineering; Elektroteknik;

   Sammanfattning : The significance of load modeling for voltage stability studies has been emphasized by several disturbances, which have taken place in the past years. They have shown that the loads in combination with other dynamics are among the main contributors of prolonged low voltage conditions, voltage instability and collapse in the power system. LÄS MER

5. 19. Cellular, Molecular and Functional Characterization of the Tumor Suppressor Candidate MYO1C

   Författare :Kittichate Visuttijai; Afrouz Behboudi; Katarina Ejeskär; Anders Oldfors; Volker Haucke; Högskolan i Skövde; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MYO1C; myosin IC; tumor suppressor gene; cancer; tumor; PI3K AKT signaling; Medical sciences; Medicin; MYO1C; myosin IC; tumor suppressor gene; cancer; tumor; PI3K AKT signaling;

   Sammanfattning : Tumor suppressor genes play a role as a growth regulator and a gatekeeper of a cell. Their inactivation is often detected in malignant tumors. Identification of novel tumor suppressor gene candidates may help to further understand tumorigenesis and aid in the discovery of a new treatment leading toward cure of cancer. LÄS MER

7. 20. The Logics of Healthcare - In Quality Improvement Work

   Författare :Christian Gadolin; Högskolan i Skövde; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; quality improvement; quality improvement work; healthcare organizations; healthcare professionals; institutional logics; institutional work; Medarbetarskap och organisatorisk resiliens FORE ; Followership and Organizational Resilience; quality improvement; quality improvement work; healthcare organizations; healthcare professionals; institutional logics; institutional work;

   Sammanfattning : Quality improvement (QI) has become a cornerstone in contemporary healthcare organizations with the aim of enabling management that facilitates efficiency and effectiveness, while providing a consistent correlation between health spending and indicators of access to and quality of care. However, despite years of reform which have attempted to change healthcare professionals’ practice, traditional professional modes of working remain relatively stable and entrenched. LÄS MER