Sökning: "icodextrin"

Hittade 4 avhandlingar innehållade ordet icodextrin.

  1. 1. Icodextrin metabolism in peritoneal dialysis : clinical and experimental studies

    Författare :Elvia García López; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Peritoneal dialysis; icodextrin; icodextrin metabolites; ultrafiltration; alphaarnylase activity; gel-filtration HPLC;

    Sammanfattning : Icodextrin (ICO, or polyglucose) is an effective osmotic agent for peritoneal dialysis (PD) patients (pts). ICO is a soluble polymeric form of glucose with an average molecular 'weight range from 13,000 to 19,000 dalton. Glucose is absorbed from the peritoneal cavity by diffusion. LÄS MER

  3. 2. Icodextrin metabolism in peritoneal dialysis : clinical and experimental studies

    Författare :Elvia Garcia Lopez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Icodextrin is a glucose polymer which is used as osmotic agent to provide sustained ultrafiltration (UF) during the long (8-16 hours) dwell in end-stage renal disease patients undergoing peritoneal dialysis (PD). The aims of this thesis were to study: the metabolism of icodextrin in the peritoneal cavity and in the circulation of PD patients and non-uremic rats, the role of alpha-amylase in its hydrolysis, and the rate of breakdown of a synthetic maltoheptaose (G7) ex vivo which we propose as a novel measure of amylase mediated oligosaccharide metabolism. LÄS MER

  4. 3. Adhesive small bowel obstruction: aspects on epidemiology, treatment, costs and prevention

    Författare :Thorbjörn B. Sakari; Filip Sköldberg; Urban Karlbom; Wilhelm Graf; Per J Nilsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small bowel obstruction; adhesions; acute surgery; colorectal cancer; Surgery; Kirurgi;

    Sammanfattning : Small bowel obstruction (SBO) is a common and sometimes life-threatening clinical condition, usually caused by post-operative adhesions. The aims of this thesis were to investigate the outcome after SBO surgery (Paper I), cost of SBO surgery including follow-up (Paper II), incidence of SBO after colorectal cancer (CRC) surgery (Paper III), and to assess the safety of using the adhesion preventing substance icodextrin in CRC surgery (Paper IV). LÄS MER

  5. 4. Pharmacokinetics and dosimetry in intraperitoneal radioimmunotherapy with 211At

    Författare :Elin Cederkrantz; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astatine-211; radioimmunotherapy; alpha-emitter; ovarian cancer; MX35; pharmacokinetics; dosimetry; effective dose;

    Sammanfattning : The prognosis for patients diagnosed with disseminated cancer is often poor. Radioimmunotherapy (RIT) is a new approach to treat disseminated disease. The aim is to target tumor cells with monoclonal antibodies (mAbs) labeled with radionuclides which release cytotoxic particle radiation upon decay. The radionuclide 211At, with half-life 7. LÄS MER