Sökning: "iNOS"
Visar resultat 16 - 20 av 112 avhandlingar innehållade ordet iNOS.
16. Regulation of inducible nitric oxide synthase - Consequences in experimental models of bladder disease
Sammanfattning : Inducible nitric oxide synthase (iNOS) expression is associated with various pathophysiological conditions in the lower urinary tract. The aims of this thesis have been to investigate the regulation of iNOS in bladder smooth muscle cells and the consequences on neuromuscular regulation, cell growth and differentiation. LÄS MER
17. Nitric oxide in brain contusion
Sammanfattning : Trauma to the brain is a leading cause of death and disability. The primary injury initiates a cascade of biochemical reactions in the brain that causes further neuronal damage, a process referred to as secondary brain injury. LÄS MER
18. Regulation of cytokine-induced nitric oxide production in insulin-producing cells
Sammanfattning : Cytokine-induced expression of the inducible form of nitric oxide synthase (iNOS) and production of nitric oxide (NO) may contribute to pancreatic β-cell damage during the development of type 1 diabetes. iNOS catalyses the conversion of arginine into citrulline and NO, a reaction regulated by the amount of expressed iNOS enzyme and by the cellular availability of arginine. LÄS MER
19. Nitric Oxide Regulation during Anti-tumor Immunotherapy
Sammanfattning : During tumor progression a strong immunosuppression is developed and is believed to be the major reason why immunotherapy fails. This suppression is induced in response to factors produced from tumor cells, but can also be induced after immunotherapy. LÄS MER
20. On the role of nitric oxide in lower urinary tract disease
Sammanfattning : Nitric oxide (NO) is an important biological molecule with a variety of functions. Among other, it is a signalling molecule capable of inducing smooth muscle relaxation and vasodilatation, it regulates proliferation, can induce apoptosis and act as an effector molecule in host defence reactions and in immune regulatory processes. LÄS MER