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Visar resultat 1 - 5 av 43 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. The limbic-hypothalamic-pituitary-adrenal axis in Alzheimer's disease

    Författare :Birgitta Näsman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; multi-infarct dementia; hippocampus; temporal lobe; adrenal androgens; adrenocorticotropin; corticotropinreleasing hormone; cortisol; skin blanching;

    Sammanfattning : Dysfunction of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis is a common finding in advanced dementia. In this study, the function of the LHPA axis at different levels was investigated in patients with dementia and in healthy elderly.A subtle disturbance in the feedback regulation of the LHPA axis was found in patients with early (i.e. LÄS MER

  3. 2. Glucocorticoid-induced adrenal insufficiency

    Författare :Margret Einarsdottir; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucocorticoid; adrenal insufficiency; mortality;

    Sammanfattning : Background: Glucocorticoids (GCs) are effective in treating many diseases and are widely used. However, glucocorticoid treatment can down-regulate the hypothalamic-pituitary-adrenal axis and lead to glucocorticoid-induced adrenal insufficiency. LÄS MER

  4. 3. Brains, genes and environment of suicide attempters

    Författare :Fredrik Vang; Lund Psykiatri; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; suicide; attempted suicide; self-injury; factor analysis; psychometrics; suicide assessment scale; cortisol; hpa-axis; hypothalamic-pituitary-adrenal axis; depression; adjustment disorder; serotonin transporter; 5HTTLPR; adversities; negative life events; globus pallidus; caudate nucleus; SPECT; MRI; volumetry; dichotic listening; brain lateralization; functional brain asymmetry;

    Sammanfattning : Identification of symptoms or biological abnormalities that predispose to suicide or identifies specific vulnerabilities, may one day improve allocation of resources or help tailor treatment to the patient. Paper I: We compared the predictive value of symptom-oriented questions against direct questions about suicidality in assessing risk for suicide attempts. LÄS MER

  5. 4. Stress system function in abdominal obesity. The hypothalamic-pituitary-adrenal axis and the sympathetic nervous system in middle-aged men

    Författare :Thomas Ljung; Göteborgs universitet; []
    Nyckelord :Abdominal obesity; stress; HPA axis; cortisol; glucocorticoid receptors; sympathetic nervous system; catecholamines; depression; SSRI;

    Sammanfattning : Background: There is a strong relationship between central (abdominal, visceral) obesity, impaired glucose tolerance, insulin resistance, dyslipidemia and elevated blood pressure. These abnormalities are included in the term Metabolic Syndrome, and indicate an elevated risk for cardiovascular disease and diabetes type 2. LÄS MER

  7. 5. Inflammation-Induced Gene Expression in Brain and Adrenal Gland

    Författare :Linda Engström; Anders Blomqvist; Tomas Hökfelt; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; brain; adrenal gland; stress; lipopolysaccharide; interleukin-1; Neurobiology; Neurobiologi;

    Sammanfattning : The autonomic nervous system serves to maintain a constant inner environment, a process termed homeostasis. Thus, in response to the homeostatic challenge posed by infectious agents, the autonomic nervous system answers to signals from the immune system and elicits adaptive physiological and behavioral reactions. LÄS MER