Sökning: "hyperplasia"

Visar resultat 1 - 5 av 179 avhandlingar innehållade ordet hyperplasia.

  1. 1. Molecular characterization of prostate hyperplasia in prolactin transgenic mice

    Författare :Karin Dillner; Göteborgs universitet; []
    Nyckelord :Prolactin-transgenic; mouse; prolactin; prostate hyperplasia; gene expression analysis;

    Sammanfattning : Benign prostatic hyperplasia (BPH) and prostate cancer are age-related diseases, affecting a majority of elderly men in the western world, and are known to be influenced by several different hormones, including sex hormones. Although the hormone prolactin (PRL) is well known to exert trophic effects on prostate cells, its involvement in the pathophysiology is still poorly characterized. LÄS MER

  3. 2. On cellular sources for intimal hyperplasia after vascular interventions

    Författare :Stefan Mellander; Göteborgs universitet; []
    Nyckelord :intimal hyperplasia; vascular intervention; smooth muscle cell; blood-born mononuclear cell; prosthetic graft; balloon injury; pig; rabbit;

    Sammanfattning : Vascular interventions for the treatment of symptomatic atherosclerosis fail in up to 40 % of the cases during the first year. One important reason is the development of a narrowing process known as intimal hyperplasia (IH). The cells forming IH resemble smooth muscle cells (SMCs) from the media of the arterial wall. LÄS MER

  4. 3. The Plasminogen Activation System in Human Endometrium and Endometrial Cancer; Function, Tissue Localization and Prognostic Importance

    Författare :Johanna Nordengren; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; progesterone; estradiol; cultured cells; gene expression; prognosis; hyperplasia; neoplasm; endometrium; human; Plasminogen activators; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Sammanfattning : The release of urokinase plasminogen activator (uPA) from endometrial stromal cells decreased after progesterone stimulation, due to upregulation of PA inhibitor 1 (PAI-1) and uPA receptor (uPAR). Subsequently, the uPA:PAI-1 complex was internalized and degraded via uPAR. LÄS MER

  5. 4. Congenital adrenal hyperplasia in adults

    Författare :Henrik Falhammar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting adrenal steroid synthesis. More than 95% of CAH cases are caused by reduced 21-hydroxylase function leading to variable extent of cortisol and aldosterone deficiency in addition to androgen excess. The foundation of CAH treatment is the use of glucocorticoids. LÄS MER

  7. 5. Adipocyte size and function in the epididymal and inguinal fat depots

    Författare :Claes Fryklund; Glukostransport och proteintrafficking; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Adipocytes; Inguinal fat; Epididymal fat; Insulin resistance; Hypertrophy; Hyperplasia;

    Sammanfattning : Nearly 60% of the worlds adult population is projected to be overweight or obese by 2030. The prevalence of obesity- related diseases, such as type 2 diabetes (T2D), has increased markedly in the past decades. The adipose tissue plays an important role in disease progression of T2D. LÄS MER