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Visar resultat 1 - 5 av 12 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. A Study of Renal Function in Children with Cancer

    Författare :Lars Hjorth; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; Pediatri; nefrologi; Urologi; nephrology; Urology; children; sequelae; pediatric oncology; chemotherapy; renal toxicity; malignancy; hyperfiltration; iohexol clearance; glomerular filtration rate; kidney disease; Glomerular proteinuria; tubular proteinuria;

    Sammanfattning : Evaluation of long-term side effects of treatment is important due to the growing number of childhood cancer survivors. How kidney function is affected over time needs to be clarified. LÄS MER

  3. 2. The Effect of Nitric Oxide and Tubuloglomerular Feedback on Renin Release and Diabetes Induced Hyperfiltration

    Författare :Johan Sällström; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  4. 3. Renal effects of C-peptide in experimental type-1 diabetes mellitus

    Författare :Björn Samnegård; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Diabetic nephropathy; C-peptide; captopril; albuminuria; glomerular hyperfiltration; glomerular hypertrophy; glomerular mesangium expansion; type-IV collagen; RAGE; renal blood flow;

    Sammanfattning : The incidence and prevalence of diabetic nephropathy are increasing continuously, mainly due to the increase in type-2 diabetes. In contrast, the risk of diabetic nephropathy for the individual patient has decreased considerably in recent decades due to improved glycemic control, successful treatment of hypertension and hyperlipidemia and the use of renin angiotensin system inhibitors, which have protective effects beyond those on blood pressure. LÄS MER

  5. 4. Functional Aspects of the Juxtaglomerular Apparatus : Control of Glomerular Filtration and Renin Release

    Författare :Johan Sällström; Erik Persson; Peter Hansell; Jürgen Schnermann; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : The juxtaglomerular apparatus (JGA) is a control unit of the kidney, that regulates glomerular filtration rate (GFR) and renin release, and hence extracellular volume and blood pressure. The tubuloglomerular feedback (TGF) mechanism is a negative feedback loop that regulates GFR. LÄS MER

  7. 5. Novel Approaches to Treatment and Prevention of Diabetic Nephropathy

    Författare :Lina Nordquist; Mats Sjöquist; Peter Bergsten; William J. Welch; Uppsala universitet; []
    Nyckelord :Physiology; Diabetes; Nephropathy; C-peptide; Microneedle; Renal; GFR; Oxygen Consumption; Reabsorption; Fysiologi;

    Sammanfattning : Several studies have reported beneficial effects of C-peptide supplementation in diabetic patients and animal models of insulinopenic diabetes. However, it is also established that good glycemic control is essential to minimize the risk of diabetes-induced complications. LÄS MER