Sökning: "hydrophobic mismatch"

Hittade 4 avhandlingar innehållade orden hydrophobic mismatch.

  1. 1. NMR diffusion studies on lyotropic liquid crystalline systems

    Författare :Greger Orädd; Frank Volke; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Diffusion; pulsed field gradient; liquid crystalline systems; lipid lateral diffusion; cubic phases; peptide-lipid interactions; hydrophobic mismatch; permeability;

    Sammanfattning : The pulsed field gradient fourier transform nuclear magnetic resonance (PFG-FTNMR) method to measure translational diffusion coefficients in multicomponent systems has been applied to amphiphilic molecules forming liquid crystalline phases.By analyzing the concentration dependence of the diffusion coefficients of water and amphiphile in a micellar system of N,N-dimethyldodecy lamine oxide (DDAO) in water it was possible to conclude that the micelles formed were polydisperse in size and shape. LÄS MER

  3. 2. Transmembrane helices : tails, turns and snorkels

    Författare :Magnus Monné; Donald Engelman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : The assembly and structure of membrane proteins are intimately related. Targeting and insertion of membrane proteins into the endoplasmatic reticulum (ER) membrane involve many components that facilitate the folding of the native structure. LÄS MER

  4. 3. Amyloid beta aggregation kinetics : The role of intrinsic and extrinsic factors

    Författare :Xiaoting Yang; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease; Abeta; aggregation; kinetics; secondary nucleation;

    Sammanfattning : Cerebral senile plaque is one of the main pathologies of Alzheimer's disease (AD). The amyloid cascade hypothesis suggests that the aggregation of amyloid beta (Abeta) peptide is involved in the pathogenesis of AD, which is supported by the fact that Abeta overexpression or production of more aggregation-prone variants lead to early-onset dementia. LÄS MER

  5. 4. Aspects of oral implant technology and osseointegration

    Författare :Rainde Naiara Rezende de Jesus; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomaterials; oral implants; surface topography; surface roughness; surface energy; surface wettability; hydrophilicity; macrogeometry; implant body; thread design; surgical protocol; oversized drilling; osseointegration; bone-to-implant contact; bone density; primary implant stability; insertion torque; removal torque; removal energy; connection stiffness; osteoclasts; RAW264.7 cells; gene expression;

    Sammanfattning : Behandling med käkbensförankrade tandimplantat är en vanlig metod för att ersätta förlorade tänder hos helt och partiellt tandlösa patienter. Trots att implantatbehandling uppvisar en långsiktigt hög lyckande- och överlevnadsfrekvens (90–95% efter 10 år) så förekommer implantatförluster och marginal benförlust kring implantaten under det första året efter insättning och/eller belastning, vilket kan försämra det estetiska resultatet. LÄS MER