Sökning: "hydrophobic binding stoichiometry"

Hittade 4 avhandlingar innehållade orden hydrophobic binding stoichiometry.

  1. 1. Microsomal glutathione transferase : studies on the kinetic mechanism, species variety, binding properties and substrate measurement

    Författare :Tie-Hua Sun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Microsomal glutathione transferase (MGST) is a membrane bound detoxification enzyme, which has been purified from different species including rat, mouse, human, frog, and fish. The rat MGST1 is localized predominantly in the liver microsomes and the outer mitochondrial membrane. LÄS MER

  3. 2. Structural and functional studies of microsomal glutathione transferase 1

    Författare :Peter J Holm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Glutathione transferase; membrane protein; three-dimensional structure; elecron crystallography; hydrophobic binding stoichiometry; H D exchange mass spectrometry;

    Sammanfattning : The microsomal glutathione transferase 1 (MGST1) is present in high amounts in the endoplasmic reticulum (ER) as an integral homo-trimeric membrane protein with a molecular weight of 51.9 kDa. LÄS MER

  4. 3. Native protein mass spectrometry of nuclear receptor-ligand and enzyme-substrate complexes

    Författare :Johan Lengqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mass spectrometry; electrospray; nuclear receptor; retinoid X receptor; fatty acid; membrane protein; glutathione transferase; glutathione;

    Sammanfattning : Nuclear receptors (NRs) are transcription factors that are activated by the binding of low molecular weight ligands. The NR superfamily includes receptors for steroid hormones, anti-inflammatory and lipid-lowering drugs as well as endogenous compounds such as bile acids and fatty acids. LÄS MER

  5. 4. Hydrogels of conjugated polyelectrolytes for biosensor and biochip applications

    Författare :Peter Åsberg; Karin D. Caldwell; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : This thesis describes the use of conjugated polyelectrolytes (CPEs) in biosensor devices. The method is based on non-covalent assembly of the biomolecule of interest and the CPE functioning as the reporter, in one case as a transducer, of biomolecular events. LÄS MER