Sökning: "hydrophilic interaction liquid chromatography"
Visar resultat 1 - 5 av 10 avhandlingar innehållade orden hydrophilic interaction liquid chromatography.
1. Hydrophilic Separation Materials for Liquid Chromatography
Sammanfattning : The main focus of this thesis is on hydrophilic interaction chromatography (HILIC) and the preparation of stationary phases for HILIC. The mechanism of HILIC is also discussed; a large part of the discussion has been adapted from a review written by me and professor Irgum for the Journal of Separation Science (ref 34). LÄS MER
2. Analytical method development in liquid chromatography- mass spectrometry based metabolomics
Sammanfattning : Metabolomics is the analytical field which aims at analyzing all small molecules, metabolites, in a biological system simultaneously. Currently no analytical methods are able to capture the entire metabolome, therefore, the analytical methods are often developed to be as general as possible. LÄS MER
3. Isocyanates, Amines and Alkanolamines : Sampling, Chromatography and Detection
Sammanfattning : Isocyanates, aromatic-, aliphatic- and alkanolamines are commonly used in the industry today. Millions of workers in Europe are exposed. The most frequent health symptoms are respiratory and dermal disorder. Due to the health risk most of the compounds in this thesis are regulated by authorities and have occupational exposure limits (OELs). LÄS MER
4. Polyhydroxyl and Polyphosphorylcholine functionalized Silica for Hydrophilic interaction liquid Chromatography- Synthesis, characterization and application
Sammanfattning : This thesis focuses on the development of new stationary phases for use in hydrophilic interaction liquid chromatography using TRIS-based and phosphorylcholine typed monomers and porous silica particles as starting substrates. In this thesis, several ways of polymerizing highly hydrophilic monomers onto pore surfaces of silica supports are described, based on several “grafting from” schemes. LÄS MER
5. Study of retention mechanisms in Hydrophilic Interaction Chromatography by Nuclear Magnetic Resonance Spectroscopy
Sammanfattning : This thesis deals with investigations of the retention mechanisms in hydrophilic interaction liquid chromatography (HILIC) using nuclear magnetic resonance spectroscopy. The aims are to understand how the different types of stationary phases can influence the retention of various solutes and the adsorption abilities of solvent on stationary phases. LÄS MER