Sökning: "hybridisation"

Visar resultat 6 - 10 av 130 avhandlingar innehållade ordet hybridisation.

  1. 6. Radiolabelled Oligonucleotides for Evaluation of in vivo Hybridisation Utilising PET Methodology

    Författare :Gábor Lendvai; Mats Bergström; Sergio Estrada; Barbro Eriksson; Raymond Josephsson; Bertrand Tavitian; Uppsala universitet; []
    Nyckelord :Molecular medicine; Gene expression; Antisense oligonucleotides; Positron emission tomography; In vivo hybridisation; In vivo biodistribution; Chromogranin-A; 68Ga; RT-PCR; Scavenger receptors; Molekylärmedicin;

    Sammanfattning : Antisense oligonucleotides (ODN) may interfere in gene expression on the basis of hybridising to its complementary messenger RNA (mRNA) sequence in the cell thereby preventing the synthesis of the peptide. Therefore, these ODNs may be potential drugs to treat human diseases by “knocking down” the expression of responsible genes or correcting the maturation process of mRNA in the field called antisense therapy. LÄS MER

  3. 7. Evolutionary history and chloroplast DNA variation in three plant genera: Betula, Corylus and Salix. : The impact of post-glacial colonisation and hybridisation

    Författare :Anna Palmé; Andrew Lowe; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; chloroplast DNA; phylogeography; hybridization; phylogeny; Salix caprea; Betula pendula; Corylus avellana; Biologi; Biology; Biologi; naturvårdsbiologi; Conservation Biology;

    Sammanfattning : The great difference in the level of chloroplast variation and its geographic structure among the three main species studied here demonstrates that forest species do not form a homogeneous group. Hazel shows a genetic structure similar to many other thermophilous species and this structure, in combination with fossil evidence, indicates that the post-glacial colonisation of most of Europe originated in a refugium in western France while the Balkan and Italy were colonised from a south-eastern refugium. LÄS MER

  4. 8. Agglutination, fusion and somatic hybridisation of plant protoplasts

    Författare :Kristina Glimelius; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  5. 9. Taxonomy and Reticulate Phylogeny of Heliosperma and Related Genera (Sileneae, Caryophyllaceae)

    Författare :Božo Frajman; Bengt Oxelman; Mats Thulin; Christian Brochmann; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sileneae; Silene; Heliosperma; Atocion; Viscaria; taxonomy; phylogenetics; relative dating; reticulate evolution; chloroplast capture; homoploid hybridisation; BEAST; r8s; PATHd8; Prometheus; RPA2; RPB2; RPD2a; RPD2b; Balkan Peninsula; endemics; Systematics and phylogenetics; Systematik och fylogeni;

    Sammanfattning : Heliosperma (nom. cons prop.) comprises 15—20 taxa, most of them endemic to the Balkan Peninsula. DNA sequences from the chloroplast (rps16 intron, psbE-petG spacer) and the nuclear genome (ITS and four putatively unlinked RNA polymerase genes) are used to elucidate phylogenetic relationships within Heliosperma, and its position within Sileneae. LÄS MER

  7. 10. Hybridisation between introduced brown hares and native mountain hares in Sweden

    Författare :Carl-Gustaf Thulin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; naturvårdsbiologi; Conservation Biology;

    Sammanfattning : To investigate the extent and effect of hybridisation between wild sympatric populations of introduced brown hares (Lepus europaeus) and native mountain hares (L.timidus) in Sweden, the geographic distribution of genetic variation in mitochondrial DNA (mtDNA) and nuclear DNA microsatellite markers were analysed within and between the two species and their presumed hybrids. LÄS MER