Sökning: "human stem cells"

Visar resultat 11 - 15 av 482 avhandlingar innehållade orden human stem cells.

  1. 11. Human neural stem cells: region-specific properties and prospects for cell therapy

    Författare :Therese Kallur; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pax6; fetal cortex and striatum; human; neural stem cells; transplantation; neurospheres; stroke; overexpression; region-specific properties;

    Sammanfattning : Cell replacement by neural transplantation can, in animal models of neurodegenerative diseases, reconstruct damaged brain circuitry. In the clinical situation, the graft material used for cell therapy must, most likely, be of human origin. LÄS MER

  3. 12. Neurogenesis from Neural Stem Cells, Ependymal Cells and Fibroblasts

    Författare :Karthikeyan Devaraju; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adult neurogenesis; stroke; neural stem cells; Lnk; ependymal cells; FoxJ1; cortical reprogramming;

    Sammanfattning : Stroke is a major cause of death and disability around the world. Stroke leads to loss of neurons and also other cells in the brain due to lack of blood supply. Currently no therapies are available to treat stroke-related disability. It has been shown that stroke leads to increased neurogenesis, birth of new neurons, within the brain. LÄS MER

  4. 13. Human articular chondrocytes. Plasticity and differentiation potentials

    Författare :Tommi Tallheden; Göteborgs universitet; []
    Nyckelord :autologous chondrocyte transplantation; dedifferentiation; redifferentiation; stem; cells;

    Sammanfattning : Articular cartilage has no or very low ability for self-repair and untreated lesions may lead tothe development of Osteoarthritis (OA). One method, which has been proved to result in longterm repair of isolated lesions, is autologous chondrocyte transplantation (ACT). LÄS MER

  5. 14. MESENCHYMAL STEM- AND STROMAL CELLS IN BONE MARROW AND OSTEOSARCOMA

    Författare :Jan Claas Brune; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; stromal cells; bone marrow stem cells; tumour stroma; stroma-directed anti-tumour therapy; osteosarcoma;

    Sammanfattning : Primary mesenchymal stem cells (MSC) play a central role in bone marrow (BM) and during haematopoiesis. Yet, the exact phenotype and spatial distribution of primary MSC in the human BM are unknown. Their cultured progeny are promising candidates for clinical applications. LÄS MER

  7. 15. Human Embryonic Stem Cells; A novel model system for early human development

    Författare :Karin Gertow; Lars Ährlund-Richter; Henrik Semb; Karolinska Institute; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human embryonic stem cells; Human embryonic stem cells; model system; differentiation; xeno-grafting; teratoma; development; karyotype; chromosomal integrity; variant.;

    Sammanfattning : Human embryonic stem cells (HESC) have since their first description in 1998 been recognized as a theoretically endless source of cells capable of differentiation into any somatic cell type. Although great attention has been given to their potential use in cell- based therapy, they are equally important as research tools for studies on early human development, both normal and diseased. LÄS MER