Sökning: "human fetal tissue"

Visar resultat 1 - 5 av 84 avhandlingar innehållade orden human fetal tissue.

  1. 1. Satellite cells in human skeletal muscle : molecular identification quantification and function

    Författare :Mona Lindström; Lars-Eric Thornell; Hannu Kalimo; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; satellite cell markers; NCAM; Pax7; MyoD; myogenin; DLK1 FA1; c-Met; human skeletal muscle; immunohistochemistry; muscle growth; muscle hypertrophy; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; anatomi; Human Anatomy;

    Sammanfattning : Skeletal muscle satellite cells located between the plasma membrane and the basal lamina of muscle fibres, could for many years, only be studied in situ by electron microscopy. The introduction of immunohistochemistry and the discovery of molecular markers of satellite cells then made them accessible for light microscopic studies and a wealth of information is today available. LÄS MER

  3. 2. Aspects of the human enteric nervous system : A study of the normal development and of Hirschsprung's disease

    Författare :Tomas Wester; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; enteric nervous system; Hirschsprung s disease; intestinal neuronal dysplasia; neuron density; nitric oxide; bcl-2; interstitial cells of Cajal; c-kit; human; fetal; development; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Thirty patients with Hirschsprung's disease (HD) who underwent Rehbein's anterior resection, using a circular stapler to perform the anastomosis, were evaluated retrospectively. The postoperative complication rate and long-term functional outcome were similar to those reported by other investigators using the same and other techniques. LÄS MER

  4. 3. The Role of Mammalian Target of Rapamycin in the Regulation of Amino Acid Transporters in the Human Placenta

    Författare :Sara Roos; Göteborgs universitet; []
    Nyckelord :amino acids; fetal growth restriction; human; mammalian target of rapamycin; membrane transporters; metabolism; placenta; pregnancy; system A; system L; taurine transporter;

    Sammanfattning : Abnormal fetal growth, which is associated with both perinatal morbidity as well as metabolic diseases in adulthood, is an important clinical problem affecting as many as 15% of all pregnancies. However, to this date, there is no specific treatment of this condition. LÄS MER

  5. 4. CELL REPLACEMENT THERAPY FOR PARKINSON’S DISEASE: The importance of neuronal subtype, cell source and connectivity for functional recovery

    Författare :Shane Grealish; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mouse behaviour; 6-hydroxydopamine; human embryonic stem cells; fetal tissue; connectivity; midbrain dopamine neuron subtype; cell transplantation; Parkinson’s disease;

    Sammanfattning : Parkinson’s disease (PD) is a neurodegenerative disorder characterised by motor deficits such as slowness in movement, difficulty in initiating movement and tremor at rest. The cause of these motor symptoms is the selective loss of mesencephalic dopaminergic (mesDA) neurons, located in the substantia nigra (SN). LÄS MER

  7. 5. Characterization of human dopaminergic neurons in the developing mesencephalon and upon differentiation of stem cells- for replacement therapy in Parkinson´s disease

    Författare :Jenny Nelander Wahlestedt; Utvecklings- och regenerativ neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson´s disease; stem cells; ventral mesencephalon; dopaminergic neurons; cell replacement therapy; human fetal tissue; radial glia; microRNA; BAC recombineering; reporter cell lines;

    Sammanfattning : Cell-replacement therapy is a promising approach for treating patients with Parkinson ́s disease (PD). For this purpose, there is a need for developing a protocol that can generate high numbers of human transplantable mesencephalic dopaminer- gic (mesDA) neurons. LÄS MER