Avancerad sökning
Hittade 4 avhandlingar som matchar ovanstående sökkriterier.
1. Enzymatic Reduction of Ketones
Sammanfattning : Methods have been studied for the production of chiral alcohols, which are of importance in organic synthesis of pharmaceuticals, agro-chemicals and fragrances, etc., through the enzymatic or microbial reduction of ketones. LÄS MER
2. Elucidation of thioredoxin reductase 1 as an anticancer drug target
Sammanfattning : Cancer constantly finds ways to survive, so we must find new ways to stop it. A major attribute of cancer cells is increased oxidative stress, occurring in the form of reactive oxygen species (ROS). Basal ROS generation commonly occurs in all types of cells and is essential for normal cellular growth and function. LÄS MER
3. Substrate specificities and functional properties of human short-chain dehydrogenases / reductases
Sammanfattning : Short-chain dehydrogenases/reductases (SDRs) constitute a universal superfamily of functionally heterogeneous proteins and participate in the metabolism of steroids, prostaglandins, retinoids, aliphatic alcohols, and xenobiotics. So far, more than 3000 members including species variants and over 60 human SDR genes are deposited in databases. LÄS MER
4. Functional genomics at the interface of protein expression and biophysical analysis
Sammanfattning : Protein characterization is central to any functional genomics effort, hence protein expression and purification play fundamental roles in these initiatives. In this study strategies for protein expression in E. coli were analysed, and several parameters were investigated respect to high-level expression of functional proteins. LÄS MER