Sökning: "human T-cells"

Visar resultat 11 - 15 av 521 avhandlingar innehållade orden human T-cells.

  1. 11. CD25+CD4+ regulatory T cells in rheumatic disease

    Författare :Duojia Cao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Human; rheumatic disease; synovial fluid; regulatory T cells; FOXP3; suppression; tolerance; autoimmunity;

    Sammanfattning : CD25+CD4+ T cells represent a unique cell lineage of thymus derived naturally occurring regulatory T cells. The gene Foxp3 (mouse)/ FOXP3(human) is strictly related to their generation in the thymus and their regulatory function in the periphery. LÄS MER

  3. 12. Insulin promotes GABA signalling modulation in both the mouse hippocampus and human CD4+ T cells

    Författare :Hayma Hammoud; Bryndis Birnir; Fredrik Elinder; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gamma-aminobutyric acid; hippocampus; tonic currents; CD4 T cells; glucose; insulin; cytokines; proliferation.; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Gamma-aminobutyric acid (GABA) is the most common inhibitory neurotransmitter in the adult mammalian brain, where it mediates several biological functions. Rapid inhibition is predominantly mediated by the activation of GABA-A receptors that are ubiquitously expressed across the central nervous system in a cell-, circuit-, or region-specific manner. LÄS MER

  4. 13. Resident T cells steer tissue responses in human skin

    Författare :Borislav Ignatov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The human skin constitutes a biological barrier against threats to the body from the surrounding environment. Tissue-resident memory cells (TRM) reside in the skin and provide local memory of previous encounters with microbes and pathogens, are poised to promptly eliminating infected cells and elicit tissue-wide defense state. LÄS MER

  5. 14. Cellular Immune Responses to Cytomegalovirus

    Författare :Anna Karin Lidehäll; Olle Korsgren; Thomas Tötterman; Ineke ten Berge; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytomegalovirus; cellular immunology; infection; immune responses; congenital infection; CD4 T cells; CD8 T cells; immunosuppressed; Clinical immunology; Klinisk immunologi;

    Sammanfattning : Cytomegalovirus (CMV) is a widespread infection affecting 50-90% of the human population. A typical silent primary infection is followed by life-long persistence in the host under control by virus-specific CD8 (“killer”) and CD4 (“helper”) T cells. LÄS MER

  7. 15. Organic dust from pig environment induces activation of human T cells

    Författare :Charlotte Müller-Suur; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Organic dust; T cells; NK cells; cytokines; cellular activation;

    Sammanfattning : Farmers suffer more frequently from inflammatory airway disorders than the population in general and a ongoing airway inflammation has been shown also in symptom-free healthy farmers. Exposure in a swine confinement building causes an intense airway inflammation with recruitment of inflammatory cells, predominately neutrophils, in healthy, previously, non-exposed subjects. LÄS MER