Sökning: "hr doktorsavhandlingar"

Visar resultat 6 - 10 av 384 avhandlingar innehållade orden hr doktorsavhandlingar.

  1. 6. New diagnostic and prognostic methods to improve the effectiveness of cervical cancer screening

    Författare :Maria Persson; Karolinska Institutet; Karolinska Institutet; []

    Sammanfattning : This thesis has made use of real-life clinical practice to provide guidance for secondary prevention of cervical cancer. We combined epidemiological, virological and biostatistical investigations using HPV DNA and HPV E6/E7 mRNA tests in women who were identified with abnormal findings through the organised cervical cancerscreening programme. LÄS MER

  2. 7. Genomic rearrangements at the cause of three genetic disorders in man

    Författare :Kristina Lagerstedt; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Mucopolysaccharidosis type II MPS II ; The Hunter syndrome; Incontinentia pigmenti IP ; Blepharophimosis; ptosis; epicanthus inversus syndrome BPES ; mutational analysis; nonhomologous end joining NHEJ ; homologous recombination HR ; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Sammanfattning : Genomic rearrangements are a common cause of genetic disorders in man. This thesis describes the analysis of genomic rearrangements observed in patients with the Hunter syndrome (MPS II), incontinentia pigmenti (IP) and the Blepharophimosis, ptosis and epicanthus inversus syndrome (BPES). MPS II is an X-linked recessive lysosomal storage disorder. LÄS MER

  3. 8. Glucotoxicity in Insulin-Producing β-Cells

    Författare :Hanna K Nyblom; Peter Bergsten; Michael Welsh; Miriam Cnop; Uppsala universitet; []
    Nyckelord :Cell biology; type 2 diabetes; SELDI-TOF MS; glucotoxicity; proteomics; insulin secretion; mitochondria; lipids; INS-1E cells; GC-MS; HR-MAS NMR; metabolomics; human islet; AMPK; AICAR; ER stress; apoptosis; Cellbiologi;

    Sammanfattning : Background and aims: Type 2 diabetes mellitus is connected with elevated glucose levels, which cause impaired glucose-stimulated insulin secretion (GSIS) and degeneration of β-cells. Mechanisms for such glucotoxic effects were explored in the present study.Materials and methods: INS-1E cells were cultured for 5 days in 5. LÄS MER

  4. 9. Surface Chemical Characteristics of Chromium-alloyed Steel Powder and the Role of Process Parameters during Sintering

    Författare :Dimitris Chasoglou; Chalmers University of Technology; []
    Nyckelord :carbothermal reaction; sintering atmosphere; depth profiling; XPS AES; HR SEM EDX; water atomized powder; surface coverage; reduction oxidation; PM steels; sintering; Cr-Mn-spinel oxides; surface oxides;

    Sammanfattning : Powder Metallurgy (PM) is a cost efficient method suitable for sustainable production of structural parts that have strict dimensional tolerances and complex geometries. It has been a common practice to utilize Ni and Cu as alloying elements in PM steels, but the high and fluctuating prices of Ni and the concerns around it associated with health hazards as well as the difficulty in recycling Cu lead the PM industry to search for effective alternatives such as Cr and Mn. LÄS MER

  5. 10. Integrated Antenna Solutions for Wireless Sensor and Millimeter-Wave Systems

    Författare :Shi Cheng; Anders Rydberg; Paul Hallbjörner; Zhining Chen; Uppsala universitet; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; harmonic radar HR ; liquid alloy; millimeter-wave; micromachining; phase shifters; planar inverted cone antennas PICA ; printed circuit boards PCB ; quasi-Yagi antennas; radio frequency microelectromechanical system RF MEMS ; stretchable antennas; substrate integrate waveguides SIW ; T-matched dipole antennas; tapered slot antennas; traveling wave array antennas; ultrawideband UWB ; wireless sensor networks.; Electrical engineering; Elektroteknik; Elektronik; Electronics;

    Sammanfattning : This thesis presents various integrated antenna solutions for different types of systems and applications, e.g. wireless sensors, broadband handsets, advanced base stations, MEMS-based reconfigurable front-ends, automotive anti-collision radars, and large area electronics. LÄS MER