Sökning: "host-pathogen interaction"

Visar resultat 16 - 20 av 33 avhandlingar innehållade orden host-pathogen interaction.

  1. 16. Studies on the host response to infection in the circulatory system

    Författare :Erik Malmström; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Sepsis is a heterogeneous, dynamic, and complex syndrome caused by interaction between the host and the invading pathogen. It is associated with an overwhelmingly dysregulated immune response, and also immunosuppression. LÄS MER

  3. 17. Mycobacterial infection: Immune evasion, host susceptibility and immunological markers of diagnostic importance

    Författare :John Arko-Mensah; Carmen Fernandez; Francesco Dieli; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacteria; Mice; Toll-like receptors; interferon gamma; immunological markers; lung; respiratory tract; susceptibility; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : IIn the first study, we investigated the functional implications of prolonged TLR signalling on IFN-γ mediated killing of mycobacteria by murine macrophages in vitro. TLR2, but not TLR4 ligation interfered with IFN-γ mediated killing of mycobacteria in macrophages. LÄS MER

  4. 18. Host-parasite interactions in space and time

    Författare :Franziska Hildebrandt; Johan Ankarklev; Volker T. Heussler; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Malaria; liver-stage infection; Toxoplasma; host-parasite interactions; spatial transcriptomics; single-cell omics; single-cell Dual-seq; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Unicellular parasites of the apicomplexan phylum have a considerable effect on global health and agriculture. Two prominent examples of this phylum include malaria causing parasites of the Plasmodium genus and the widely prevalent parasite Toxoplasma gondii. LÄS MER

  5. 19. "A syndrome so characteristic" Molecular and clinical studies of Fusobacterium necrophorum and Lemierre's syndrome

    Författare :Karin Holm; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Fusobacterium necrophorum; Lemierre’s syndrome; contact system; fibrinolysis; thrombophilia; leukotoxin;

    Sammanfattning : Lemierre’s syndrome is caused by Fusobacterium necrophorum and involves tonsillitis, jugular vein thrombophlebitis and septic pulmonary emboli. The first studies underlying this thesis focused on bacterial interaction with coagulation. LÄS MER

  7. 20. Viruses on the wing : evolution and dynamics of influenza A virus in the Mallard reservoir

    Författare :Michelle Wille; Jonas Waldenström; Timm Harder; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Co-infections; Ecology; Epidemiology; Evolution; Host-Parasite Interactions; Immunity; Influenza A Virus; Mallard; Phylogeny; Virology; Waterfowl; Wild Birds; Wildlife Disease; Zoonotisk ekologi; Zoonotic Ecology;

    Sammanfattning : This thesis explores the evolution of avian influenza A viruses (IAV), as well as host-pathogen interactions between these viruses and their main reservoir host, the Mallard (Anas platyrhynchos). IAV is a genetically diverse, multi-host virus and wild birds, particularly dabbling ducks, are the natural reservoir. LÄS MER