Sökning: "host-adaptation"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet host-adaptation.

  1. 1. Proteomic profiling of bacterial host adaptation : Racing the Red Queen

    Författare :Ola Kilsgård; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; Mass Spectrometry; Systems biology; Biomarker; Host adaptation; Bacteria; Streptococcus pyogenes;

    Sammanfattning : Despite the discovery of antibiotics almost a century ago, infectious diseases continue to be a substantial cause of human mortality and morbidity worldwide, especially in developing countries. The adverse affects of infectious diseases are thought to increase over the coming years as the widespread misuse of antibiotic leads to the emergence of strains for which current therapies are ineffective. LÄS MER

  3. 2. Genome Evolution and Host Adaptation in Bartonella

    Författare :Eva Caroline Berglund; Siv GE Andersson; Brendan Wren; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bartonella; genome evolution; genome diversity; phage; gene transfer agent; secretion system; microarray; Bioinformatics; Bioinformatik; Evolutionary Genetics; evolutionär genetik;

    Sammanfattning : Bacteria of the genus Bartonella infect the red blood cells of a wide range of wild and domestic mammals and are transmitted between hosts by blood-sucking insects. Although most Bartonella infections are asymptomatic, the genus contains several human pathogens. LÄS MER

  4. 3. Evolution and host-specific adaptations of Legionella pneumophila

    Författare :Anaísa B. Moreno; Lionel Guy; Dan I. Andersson; Fredrik Söderbom; Alexander W. Ensminger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Evolution; Legionella pneumophila; host-adaptation; experimental evolution; Acanthamoeba castellanii; transfection; Mikrobiologi; Microbiology;

    Sammanfattning : How bacteria evolve pathogenic traits is shaped by their communities and environments. Legionella pneumophila is ubiquitous in aquatic habitats, where it persists by replicating within a broad range of protozoan hosts. Using the same mechanisms, L. LÄS MER

  5. 4. Proteome-wide analysis of severe bacterial infections. The battle between host and pathogen

    Författare :Anahita Bakochi; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; Mass Spectrometry; Systems biology; Host adaptation; Meningitis; Streptococcus pneumoniae;

    Sammanfattning : The pathogenesis of severe infectious diseases is a complex interplay between the host and the pathogen. The development and progression of a disease encompasses a multitude of processes, which balance between host-damage and host-protection. LÄS MER

  7. 5. Genetic adaptation of salmonella enterica to phagocytic cells

    Författare :Sofia Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Salmonella; macrophages; host-adaptation; microarray; nitric oxide;

    Sammanfattning : Salmonella enterica is a collection of closely related enteric bacteria that as a species is capable of infecting a wide variety of hosts. S. enterica serovar Typhimurium, (S. Typhimurium), causes a systemic disease in mice which in many aspects resembles human typhoid fever caused by S. LÄS MER