Sökning: "host microbiota"

Visar resultat 21 - 25 av 84 avhandlingar innehållade orden host microbiota.

1. 21. Development of chemical biology tools for metabolomics analysis : Phase II modifications as a link between host and microbiota co-metabolism

   Författare :Mario S. P. Correia; Daniel Globisch; Warwick Dunn; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolomics; Chemical biology; sulfatase; Glucuronides; Phase II modifications; Microbiome; co-metabolism; method development; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

   Sammanfattning : Biomarker discovery is an extremely important field for early disease detection. New selective molecular markers are in high demand, as an earlier disease detection can lead to improved patient care. LÄS MER

3. 22. Interplay between bacteria and host epithelial cells

   Författare :Lisa Maudsdotter; Ann-Beth Jonsson; Cindy Grove Arvidson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbial-cell interaction; Adherence; Infection; Lactic acid bacteria; Antimicrobial peptides; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Bacterial pathogens have developed multiple ways of manipulating host cell functions to exploit the host environment. We found that interactions with epithelial cells increase the resistance of the human pathogen Neisseria meningitidis to the antimicrobial peptide LL-37. LÄS MER

4. 23. Pathogenic Neisseria infections of human neutrophils and epithelial cells : focusing on host responses and immune evasion

   Författare :Niklas Söderholm; Helena Aro; Thomas Rudel; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; Neisseria gonorrhoeae; Neutrophils; PMN; Epithelial cells; Polarized cells; Type IV pili; Adherence; Cell cycle; DNA damage; Lactobacillus; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : N. meningitidis and N. gonorrhoeae are obligate human pathogens that colonize mucosal surfaces and are often carried asymptomatically. These bacteria have developed adhesive structures that promote adherence to host cells and efficient colonization of new hosts. LÄS MER

5. 24. Host Immunity-Microbiota-Virus Interactions at the Intestinal Mucosal surface in Health and Disease

   Författare :Kedir Hamza; Virusrekognition; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The presence of viral immune triggers at the intestinal mucosa can have multipleglobal effects on intestinal integrity, including relative protection fromsubsequent inflammatory bowel disease. During the last century, the westernworld has achieved a remarkable success in preventing infectious diseases,which increased the general life expectancy dramatically. LÄS MER

7. 25. The human gastric microbiota in health and disease

   Författare :Mathilda Lindberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The human body comprises of complex microbial ecosystems that have co-evolved with its host and play important roles in the maintenance of health and in the etiology and outcome of various disease states. The microbiota that resides in the stomach has not been completely identified, and focus has previously been mainly on the gastric pathogen Helicobacter pylori. LÄS MER