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  1. 1. Ecology and evolution in a host-parasitoid system : Host search, immune responses and parasitoid virulence

    Författare :Lisa Fors; Peter Hambäck; Wertheim Bregje; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Host-parasitoid interactions; Plant-herbivore interactions; Host search; Volatiles; Pheromones; Geographic variation; Cellular defence; Melanisation; Encapsulation; Asecodes; Galerucella; Plant Ecology; växtekologi;

    Sammanfattning : In host-parasitoid systems, there is a continuous coevolutionary arms race where each species imposes a strong selection pressure on the other. The host needs to develop defence strategies in order to escape parasitism and the parasitoid must evolve counter-defence strategies in order to overcome the host’s immune defence and successfully reproduce. LÄS MER

  3. 2. Functional dualism of antimicrobial host defence peptides

    Författare :Åse Björstad; Göteborgs universitet; []
    Nyckelord :antimicrobial; apoptosis; cathelicidin; host defence peptide; interleukin 8; LL-37; permeabilisation;

    Sammanfattning : Antimicrobial host defence peptides are central to innate immunity and many possess direct antimicrobial actions on bacteria as well as indirect immunomodulatory functions on human leukocytes. Different variants of the bifunctional Helicobacter pylori peptide, Hp(2-20), were synthesised and inhibition zone assays and chemiluminescence systems were employed for determination of direct antimicrobial action and superoxide release (immunomodulatory) from human neutrophils, respectively. LÄS MER

  4. 3. Midkine - a host defence protein

    Författare :Sara Nordin; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antimicrobial polypeptides; Midkine; antibacterial; antifungal; innate immunity; epithelial surfaces;

    Sammanfattning : Every day we encounter many potentially harmful microbes in our environment. The epithelial linings constitute an anatomical barrier protecting us and they also produce antimicrobial polypeptides (AMPs) that act as a chemical barrier. These AMPs are small and positively charged, killing a broad range of microbes rapidly. LÄS MER

  5. 4. Novel Aspects of the Coagulation System in Host Defence

    Författare :Praveen Papareddy; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Host defence peptides; Coagulation system; Sepsis; Thrombin; TFPI-1; TFPI-2; HCII;

    Sammanfattning : Bacterial infections are a major global threat to public health and sepsis is a major cause of morbidity and mortality. Sepsis incidence is rising, with supportive treatments and antibiotics being the main treatment possibilities. LÄS MER

  7. 5. Drosophila-Serratia as a host-parasite system : defence mechanisms and virulence factors

    Författare :Casper Flyg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER