Sökning: "host cell"

Visar resultat 1 - 5 av 1061 avhandlingar innehållade orden host cell.

  1. 1. Unique Solutions to Universal Problems : Studies of the Archaeal Cell

    Författare :Erik A. Pelve; Rolf Bernander; Sonja Verena Albers; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Archaea; Cdv; Cell cycle; Cell division; Cell lysis; Crenarchaea; ESCRT-III; Flow cytometry; Microarray; Microscopy; Nitrosopumilus; SIRV2; Sulfolobus; Thaumarchaea; Transcription; VAP; Virus; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

    Sammanfattning : Archaea is one of the three domains of life and studies of archaeal biology are important for understanding of life in extreme environments, fundamental biogeochemical processes, the origin of life, the eukaryotic cell and their own, unique biology. This thesis presents four studies of the archaeal cell, using the extremophilic Sulfolobus and ocean living Nitrosopumilus as model systems. LÄS MER

  3. 2. Host-bacteria interactions : Host cell responses and bacterial pathogenesis

    Författare :Nele de Klerk; Ann-Beth Jonsson; Teresa Frisan; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Host-bacteria interaction; Helicobacter pylori; Neisseria gonorrhoeae; Lactobacillus; Epithelial cells; Macrophages; EGR1; Amphiregulin; SabA; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Helicobacter pylori colonizes the human stomach, where it causes gastritis that may develop into peptic ulcer disease or cancer when left untreated. Neisseria gonorrhoeae colonizes the urogenital tract and causes the sexually transmitted disease gonorrhea. LÄS MER

  4. 3. Molecular Studies of Mast Cell Migration and Apoptosis : Two Ways of Regulating Mast Cell Numbers at Sites of Inflammation

    Författare :Jessica Alfredsson; Gunnar Nilsson; Hans-Uwe Simon; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; mast cell; SCF; IL-3; FcεRI; migration; apoptosis; Bim; Bcl-2; Bcl-XL; Akt; FOXO; MAPK; Patologi; Pathology; Patologi;

    Sammanfattning : Upon activation mast cells release numerous proinflammatory mediators. With this feature, mast cells play an important role in host defense against pathogens, and are involved in tissue remodeling and wound healing. However, in cases of excessive inflammation the effects of mast cells are detrimental. LÄS MER

  5. 4. Roles of secreted bacterial factors in modulation of host cell signalling

    Författare :Eric Toh; Sun Nyunt Wai; Teresa Frisan; Staffan Bohm; Ann-Beth Jonsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria-host interaction; motility-associated killing factor A; outer membrane vesicles; cytolysin A; phosphatidylinositol 4-phosphate 5-kinase alpha; enhancer of zeste homologue 2; epigenetic modulation; Medical Cell Biology; medicinsk cellbiologi; mikrobiologi; Microbiology;

    Sammanfattning : Pathogenic bacteria employ several secretion systems to release or inject virulence factors that may alter host cell processes, generate a replicative niche, and aid bacterial survival in adverse environments. This thesis presents my investigations on how bacterial factors can modulate host cell signalling mechanisms. LÄS MER

  7. 5. Bacteria-host cell interactions : Studies on initial colonization, antimicrobial peptides, and biofilms

    Författare :Gabriela Wassing; Ann-Beth Jonsson; Elena Vikström; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; Lactobacillus; host responses; EGR1; antimicrobial peptides; hBD2; A20; biofilm; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The obligate human pathogen Neisseria meningitidis asymptomatically colonizes the upper respiratory tract, but crossing of the epithelial barrier can cause life-threatening meningitis and/or sepsis. N. LÄS MER