Sökning: "horn effect"

Visar resultat 1 - 5 av 37 avhandlingar innehållade orden horn effect.

  1. 1. Cytoskeleton-interacting proteins in brainstem development : roles of KCC2 and Vangl2

    Författare :Zachi Horn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The brainstem is the most evolutionary conserved division of the brain. It develops from the hindbrain and midbrain regions of the neural tube and forms neural networks that regulate vital functions of the body. One of the most critical roles is to generate respiratory rhythm for the regulation of oxygen, carbon dioxide and pH levels. LÄS MER

  3. 2. Early function of KCC2 and Wnt genes : cytoskeletal effects in neural stem cells

    Författare :Zachi Horn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : From closure of the neural tube until formation of neuronal networks, cells undergo several crucial changes which depend on the expression of many important molecules. GABA, the principal inhibitory neurotransmitter in the adult nervous system, acts as an excitatory signal during embryonic development. LÄS MER

  4. 3. Regulation of insulin-like growth factor-II in human liver

    Författare :Henrik von Horn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :IG17-II; IGF2; IGFBPs; liver; hepatoblastoma; GH; hypoxia;

    Sammanfattning : Insulin-like growth factors-I and -II (IGF-I and -II) are mitogens in a number of cell types and also have insulin-like actions. IGF-II has an autocrine role in a variety of malignancies; and hypoglycemia is well documented in conditions associated with elevated IGF-II precursor forms in the circulation. LÄS MER

  5. 4. Drug discovery against leishmaniasis : Bio- and chemoinformatic guided strategies for target evaluation and hit identification

    Författare :Elisabet Vikeved; UCM Alsmark; Christian Sköld; David Horn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leishmaniasis; Drug discovery; Lateral gene transfer; Comparative genomics; Virtual screening; Target fishing; Marine natural products;

    Sammanfattning : Leishmaniasis is a neglected tropical disease mainly affecting poor people in developing countries. It is caused by infections of flagellated protozoa belonging to genus Leishmania. The few available drugs are associated with problems such as low effectiveness, severe side effects and resistance development. LÄS MER

  7. 5. Atomic and Electronic Structures of Clean and Metal Adsorbed Si and Ge Surfaces : An Experimental and Theoretical Study

    Författare :Johan Eriksson; Roger Uhrberg; Karsten Horn; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : In this work, a selection of unresolved topics regarding the electronic and atomic structures of Si and Ge surfaces, both clean ones and those modified by metal adsorbates, are addressed. The results presented have been obtained using theoretical calculations and experimental techniques such as photoelectron spectroscopy (PES), low energy electron diffraction (LEED) and scanning tunneling microscopy (STM). LÄS MER