Sökning: "homogeneous assays"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden homogeneous assays.

  1. 1. Magnetic Nanoparticle Based Biosensors for Pathogen Detection and Cancer Diagnostics

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Bo Tian; Uppsala universitet.; [2018]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic biosensors; magnetic nanoparticles; homogeneous assays; volumetric sensing; Engineering Science with specialization in Solid State Physics; Teknisk fysik med inriktning mot fasta tillståndets fysik;

    Sammanfattning : This thesis describes several magnetic nanoparticle (MNP)-based biosensing strategies which take advantage of different magnetic sensors, molecular tools and nanotechnologies. Proposed biosensors can be classified into three groups, i.e., immunoassay-based, molecular amplification-based, and nanoparticle assembly-based. LÄS MER

  2. 2. Ultrasonic Enrichment of Microparticles in Bioaffinity Assays

    Detta är en avhandling från Stockholm : Fysik

    Författare :Martin Wiklund; KTH.; [2004]
    Nyckelord :analytical chemistry; biochemistry; acoustics; biomedical engineering;

    Sammanfattning : This Thesis describes applications of standing-waveultrasonic traps for sensitive biomedical analysis. Two majorapproaches have been investigated where functionalizedmicroparticles are employed in bioaffinity assays. LÄS MER

  3. 3. Development and Application of Triple Specific Proximity Ligation Assays (3PLA)

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Edith Schallmeiner; Uppsala universitet.; [2007]
    Nyckelord :Molecular medicine; proxmity ligation; method development; cell siganling; Molekylärmedicin;

    Sammanfattning : After the completion of the human genome project the human genome was annotated with the surprisingly small amount of 24 000 (www.ensemble.com) genes. LÄS MER

  4. 4. Fluorescence-based ligand assays for protein detection using affibody affinity proteins

    Detta är en avhandling från Stockholm : KTH

    Författare :Björn Renberg; KTH.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Affibody molecules; biosensors; FRET; immobilisation; solid-phase synthesis; protein microarrays; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi;

    Sammanfattning : The detection and quantification of biomolecules, and proteins in particular, are of great interest since these molecules are of fundamental importance to our well-being. Body fluids, as for instance human blood, are well suited for sampling of protein levels. LÄS MER

  5. 5. Sensitivity, Noise and Detection of Enzyme Inhibition in Progress Curves

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Omar Gutierrez Arenas; Uppsala universitet.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Progress curves; limit of detection; Z -factor; primary screening; enzyme inhibition; error structure; sensitivity analysis; High-throughput screning; Biokemi;

    Sammanfattning : Starting with the development of an enzymatic assay, where an enzyme in solution hydrolysed a solid-phase bound peptide, a model for the kinetics of enzyme action was introduced. This model allowed the estimation of kinetic parameters and enzyme activity for a system that has the peculiarity of not being saturable with the substrate, but with the enzyme. LÄS MER