Sökning: "homogeneous assays"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden homogeneous assays.

  1. 1. Further development of light-up probes : dye synthesis and PCR applications

    Författare :Jennie Isacsson; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; asymmetric cyanine dyes; homogeneous assays; flourecent hybridisation probes; light-up probes; peptide nucleic acids; PCS; solid phase synthesis; LightUp probe;

    Sammanfattning : .... LÄS MER

  3. 2. Magnetic Nanoparticle Based Biosensors for Pathogen Detection and Cancer Diagnostics

    Författare :Bo Tian; Mattias Strömberg; Peter Svedlindh; Hakho Lee; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic biosensors; magnetic nanoparticles; homogeneous assays; volumetric sensing; Engineering Science with specialization in Solid State Physics; Teknisk fysik med inriktning mot fasta tillståndets fysik;

    Sammanfattning : This thesis describes several magnetic nanoparticle (MNP)-based biosensing strategies which take advantage of different magnetic sensors, molecular tools and nanotechnologies. Proposed biosensors can be classified into three groups, i.e., immunoassay-based, molecular amplification-based, and nanoparticle assembly-based. LÄS MER

  4. 3. Ultrasonic Enrichment of Microparticles in Bioaffinity Assays

    Författare :Martin Wiklund; KTH; []
    Nyckelord :analytical chemistry; biochemistry; acoustics; biomedical engineering;

    Sammanfattning : This Thesis describes applications of standing-waveultrasonic traps for sensitive biomedical analysis. Two majorapproaches have been investigated where functionalizedmicroparticles are employed in bioaffinity assays. LÄS MER

  5. 4. The Light-up Probe

    Författare :Nicke Svanvik; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; asymmetric cyanine dyes; light-up probes; PNA; real-time PCR; LightUp Probe; fluorescent hybridization probes; homogeneous hybridization assays;

    Sammanfattning : The work presented in this thesis concerns the development of light-up probes and their potential applications in PCR based molecular diagnostics. The light-up probe is a nucleic acid analog (here PNA) oligomer linked to an asymmetric cyanine dye (here thiazole orange) and it combines the excellent hybridization properties of PNA with the large fluorescence enhancement of the dye upon binding to DNA. LÄS MER

  7. 5. Development and Application of Triple Specific Proximity Ligation Assays (3PLA)

    Författare :Edith Schallmeiner; Ulf Landegren; Larry Gold; Uppsala universitet; []
    Nyckelord :Molecular medicine; proxmity ligation; method development; cell siganling; Molekylärmedicin;

    Sammanfattning : After the completion of the human genome project the human genome was annotated with the surprisingly small amount of 24 000 (www.ensemble.com) genes. LÄS MER