Sökning: "homoallylic"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet homoallylic.

  1. 1. Catalytic Regio- and Stereoselective Reactions for the Synthesis of Allylic and Homoallylic Compounds

    Författare :Rauful Alam; Kalman Szabo; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; palladium catalysis; C−H functionalization; boronic acid; allylboration; asymmetric catalysis; allylic; homoallylic; diastereoselective; enantioselective; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis is focused on two main areas of organic synthesis, palladium-catalyzed functionalization of alkenes and allylic alcohols, as well as development of new allylboration reactions.We have developed a palladium-catalyzed selective allylic trifluoroacetoxylation reaction based on C−H functionalization. LÄS MER

  3. 2. Novel Pincer Complex-Catalyzed Transformations : Including Asymmetric Catalysis

    Författare :Juhanes Aydin; Kálmán J. Szabó; Oleg V. Ozerov; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; pincer; palladium; catalysis; chiral; asymmetric; palladium IV; allylation; aldol; aminoacid; C-H functionalization; cross-coupling; homoallylic; heck reaction; tridentate ligand; Chemistry; Kemi; Organic Chemistry; organisk kemi;

    Sammanfattning : This thesis is focused on the development of new pincer complex-catalyzed transformations. Optimization of the catalytic properties (fine-tuning) was directed to increase the catalytic activity as well as the chemo-, stereo- and enantioselectivity of the complexes. LÄS MER

  4. 3. Asymmetric [2,3]-Sigmatropic Rearrangement of Allylic Ammonium Ylides

    Författare :Jan Blid; Peter Somfai; James C. Anderson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; asymmetric; [2; 3]-sigmatropic rearrangement; allylic amine; ammonium ylide; Lewis acid; enantioselective; boron; phosphazene base; NMR spectroscopy; DFT-calculations; Organic chemistry; Organisk kemi;

    Sammanfattning : The thesis describes the realization of an asymmetric [2,3]-sigmatropic rearrangement of achiral allylic amines. It is divided into two parts; the first part deals with the development of a Lewis acid-mediated [2,3]-sigmatropic rearrangement and the second the asymmetric version thereof. LÄS MER

  5. 4. Ruthenium-Catalyzed Hydrogen Transfer Reactions : Mechanistic Studies and Chemoenzymatic Dynamic Kinetic Resolutions

    Författare :Madeleine Warner; Jan-Erling Bäckvall; Andreas Pfaltz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hydrogen transfer; ruthenium catalysis; kinetic resolution; dynamic kinetic resolution; racemization; asymmetric synthesis; organisk kemi; Organic Chemistry;

    Sammanfattning : The main focus of this thesis lies on transition metal-catalyzed hydrogen transfer reactions. In the first part of the thesis, the mechanism for racemization of sec-alcohols with a ruthenium complex, Ru(CO)2Cl(η5-C5Ph5) was studied. LÄS MER

  7. 5. Design and stereoselective syntheses of Phe-Phe dipeptidomimetics

    Författare :Annika Jenmalm Jensen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

    Sammanfattning : Several stereochemically well characterized Phe-Phe dipeptidomimetics have been designed and synthesized. The Phe-Phe vinyl isostere was used as a key intermediate. The synthesized series of mimetics includes two isomeric epoxides, four 1,2-dihydroxyethylene isomers, two isomeric allylic alcohols and two isomeric allylic fluorides. LÄS MER