Sökning: "hober"

Visar resultat 1 - 5 av 24 avhandlingar innehållade ordet hober.

  1. 1. Development of novel affinity enrichment strategies for clinical applications using selected reaction monitoring

    Författare :Andreas Hober; Mathias Uhlén; Fredrik Edfors; Björn Forsström; Johan Malmström; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; proteomics; mass spectrometry; selected reaction monitoring; absolute quantification; antibody validation; precision medicine; Biotechnology; Bioteknologi;

    Sammanfattning : Proteins are key components of any living organism and an essential part of life itself. They can provide cells with structure and perform life-sustaining intracellular reactions. As organisms grow more complex, this task expands even further. LÄS MER

  3. 2. Interaction engineered three-helix bundle domains for protein recovery and detection

    Författare :Tove Alm; Sophia Hober; Rainer Hahn; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ABD; Zbasic; albumin; protein engineering; phage display; staphylococcal display; inclusion bodies; refolding; proteomics; orthogonal affinity purification; Bioengineering; Bioteknik; Immunology engineering; Immunteknik;

    Sammanfattning : HTML clipboard The great advances in DNA technology, e.g. sequencing and recombinant DNA techniques, have given us the genetic information and the tools needed to effectively produce recombinant proteins. Recombinant proteins are valuable means in biotechnological applications and are also emerging as alternatives in therapeutic applications. LÄS MER

  4. 3. Studies of Enterovirus Infection and Induction of Innate Immunity in Human Pancreatic Cells

    Författare :Mahesh Anagandula; Magnus Essand; Didier Hober; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; Enterovirus; Innate Immunity; Pancreas;

    Sammanfattning : Several epidemiological and clinical studies have indicated a possible role of Enterovirus (EV) infection in type 1 diabetes (T1D) development. However, the exact casual mechanism of these viruses in T1D development is not known. LÄS MER

  5. 4. High-throughput protein analysis using mass spectrometry-based methods

    Författare :Tove Boström; Sophia Hober; Thomas Laurell; Ole N. Jensen; KTH; []
    Nyckelord :Proteomics; mass spectrometry; affinity proteomics; immunoenrichment; immunoprecipitation; IMAC; screening; protein production; protein purification; ISET; quantification; SILAC; stable isotope standard; antibody validation; Bioteknologi; Biotechnology;

    Sammanfattning : In the field of proteomics, proteins are analyzed and quantified in high numbers. Protein analysis is of great importance and can for example generate information regarding protein function and involvement in disease. Different strategies for protein analysis and quan- tification have emerged, suitable for different applications. LÄS MER

  7. 5. The Use of “non-ICSID” Arbitration Rules in Investment Treaty Disputes : Domestic Courts, Commercial Arbitration Institutions and Arbitral Tribunal Jurisdiction

    Författare :Joel Dahlquist Cullborg; Kaj Hobér; Iain Cameron; Freya Baetens; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; International investment law; international arbitration; investment treaties; BIT; ICSID; UNCITRAL; jurisdiction; treaty interpretation; emergency arbitration; Iran-United States Claims Tribunal; Public International Law; Folkrätt;

    Sammanfattning : This book studies how domestic courts and commercial arbitration institutions impact the scope of arbitral tribunal jurisdiction in investment treaty disputes. Arbitration clauses in investment treaties often provide investors with a choice between ICSID arbitration and rules originally drafted for commercial arbitration. LÄS MER