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Visar resultat 1 - 5 av 23 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Molecular and structural patterns of guided bone regeneration (GBR). Experimental studies on the role of GBR membrane and bone substitute materials

   Författare :Ibrahim Elgali; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regenerative medicine; biomaterials; bone substitute; calcium phosphate; guided bone regeneration; membrane; strontium; bone defect; bone remodeling; inflammation; cytokines; chemokines; growth factors; gene expression; histomorphometry; in vivo;

   Sammanfattning : The mechanisms of guided bone regeneration (GBR) and bone healing with calcium phosphate (CaP) bone substitutes are not fully understood. The major aim of this thesis was to determine the relationship between the bone formation in bone defects and the cellular distribution and activities in association with CaP materials and/or with GBR membrane. LÄS MER

3. 2. A methodological platform to study molecular biocompatibility of biomaterials. Experimental and clinical studies

   Författare :Maria Lennerås; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osseointegration; titanium; inflammation; cell recruitment; cell adhesion; bone regeneration; bone remodelling; gene expression; immunohistochemistry; histomorphometry; removal torque; ultrastructure; FACS; protein profiling; transfemoral amputation; abutment; percutaneous; bacteria; clinical signs;

   Sammanfattning : The aim of this project was to develop a methodological platform in order to advance our scientific understanding of the mechanisms of osseointegration. Screw-shaped, titanium implants, with different surface properties, were inserted in the rat tibia, or incubated in mono- or co-culture of human monocytes and MSCs. LÄS MER

4. 3. On 606 retrieved oral and cranio-facial implants. An analysis of consecutively received human specimens

   Författare :Pia Bolind; Göteborgs universitet; []
   Nyckelord :retrieved human implants; oral; craniofacial; bone; undecalcified sections; histology; histomorphometry;

   Sammanfattning : Aim:The aim of the present thesis was to histologically and histomorphometrically analyse retrieved human specimens of oral and cranio-facial implants, and to address the clinical relevance of a retrieval bank.Materials and methods:The specimens analysed were submitted to the retrieval bank at the Department of Biomaterials / Handicap Research. LÄS MER

5. 4. Effects of antiresorptive agents on inflammation and bone regeneration in different osseous sites - experimental and clinical studies

   Författare :Carina Cardemil; Peter Thomsen; Cecilia Larsson Wexell; Bente Brokstad Herlofson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Qntiresorptive agents; ovariectomised rat; osteoporosis; skeletal site; differences osteonecrosis of the jaw; osseointegration; bone substitute; inflammation; bone regeneration; gene expression; histomorphometry; Micro-CT; antiresorptive agents; ovariectomised rat; osteoporosis; skeletal site differences; osteonecrosis of the jaw; osseointegration; bone substitute; inflammation; bone regeneration; gene expression; histomorphometry; Micro-CT;

   Sammanfattning : The biological mechanisms involved in bone regeneration in osteoporotic bone and the effect of antiresorptive drugs in relation to surgically inserted biomaterials are not fully understood. Improved osseointegration of titanium implants but also adverse effects of antiresorptive therapies, such as osteonecrotic jaw have been described in the literature. LÄS MER

7. 5. On the tissue response to hafnium, titanium and thin calcium phosphate coatings

   Författare :Sham Mohammadi; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hafnium; titanium; calcium phosphates; hydroxyapatite; implants; bone; soft tissue; histomorphometry;

   Sammanfattning : Background: Titanium (Ti) is the gold standard material for load-bearing implants. Although high success rates have been reported for Ti implants, failures do occur. Alternative materials/surface modifications might further improve the performances of Ti implants, particularly in situations with non-optimal local tissue conditions. LÄS MER