Sökning: "hippocampus"

Visar resultat 16 - 20 av 383 avhandlingar innehållade ordet hippocampus.

  1. 16. Gene therapy in epilepsy: neuropeptides and neurotrophic factors

    Författare :Irene Kanter Schlifke; Lund Wallenberg Neurocentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; piriform cortex; hippocampus; neuropsykologi; encapsulated cells; viral vectors; GDNF; galanin; epilepsy; gene therapy; neurofysiologi;

    Sammanfattning : Temporal lobe epilepsy (TLE) is the most common form of epilepsy among adult patients, and the most problematic one as seizures cannot be controlled by currently available drugs in 30 % of patients. Gene therapy based on overexpression of endogenous anti-epileptic agents such as the neuropeptide galanin and the glial cell line-derived neurotrophic factor (GDNF) represents a promising new approach for treatment of TLE. LÄS MER

  3. 17. Neurogenesis in the adult brain from ballyhoo to sobriety

    Författare :Helena Frielingsdorf; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurofysiologi; Neurologi; neurophysiology; neuropsychology; Neurology; Nerve growth factor; acetylcholine; GABA; learning; hippocampus; Neurogenesis; dopamine; substantia nigra;

    Sammanfattning : New neurons are spontaneously generated in two regions of the adult brain, the hippocampus and the subventricular zone/olfactory bulb. The objective of this thesis was to study potential implications for adult neurogenesis in Alzheimer's (AD) and Parkinson's diseases (PD). LÄS MER

  4. 18. The effect of astrocytes and reactive gliosis on neurogenesis and astrogenesis in mice

    Författare :Åsa Widestrand; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astrocytes; intermediate filaments; neural stem cells; neurogenesis; astrogenesis; hippocampus;

    Sammanfattning : Astrocytes are the most common cell type in mammalian central nervous system (CNS). Glial fibrillary acidic protein (GFAP) and vimentin constitute intermediate filaments (known also as nanofilaments), a part of the cytoskeleton, in astrocytes. LÄS MER

  5. 19. Cerebral arterial pulsatility imaging using 4D flow MRI : methodological development and applications in brain aging

    Författare :Tomas Vikner; Anders Wåhlin; Anders Eklund; Jan Malm; Lars Nyberg; Susanne Schnell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; 4D flow MRI; medical image analysis; cerebral hemodynamics; arterial pulsatility; DCE MRI; blood-brain barrier; white matter lesions; perivascular spaces; cerebral small vessel disease; hippocampus; cognition; aging; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Sammanfattning : 4D flow magnetic resonance imaging (MRI) is increasingly recognizedas a versatile tool to assess arterial and venous hemodynamics. Cerebral arterial pulsatility is typically assessed by analyzing flow waveforms over the cardiac cycle, where flow amplitude is a function of cardiac output, central arterial stiffness, and cerebrovascular resistance and compliance. LÄS MER

  7. 20. Radiological Studies on Hippocampal Development : Morphological Variants and their Relationship to Epilepsy

    Författare :Dragan Bajic; Raili Raininko; Kai Ericson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MRI; Brain development; Hippocampus; Epilepsy; Radiology; Radiologi; Radiologi; Radiology;

    Sammanfattning : During fetal development, the hippocampal structures are folded forming the hippocampal sulcus which penetrates into the temporal lobe and then the entity rotates.  During this process, the hippocampal sulcus will be closed and the inverted hippocampus takes a rounded form. LÄS MER