Sökning: "higher-order networks"

Visar resultat 1 - 5 av 27 avhandlingar innehållade orden higher-order networks.

  1. 1. Toward higher-order network models

    Författare :Ludvig Bohlin; Martin Rosvall; Ludvig Lizana; Tina Eliassi-Rad; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; network science; complex systems; complex networks; network analysis; higher-order networks; community detection; citation networks; network modeling; fysik; Physics;

    Sammanfattning : Complex systems play an essential role in our daily lives. These systems consist of many connected components that interact with each other. LÄS MER

  3. 2. Mapping higher-order dynamics and interactions in complex networks

    Författare :Anton Holmgren; Martin Rosvall; Ludvig Lizana; Ingo Scholtes; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; networks; community detection; information theory; the map equation;

    Sammanfattning : Complex systems research seeks to explain emergent properties in social, technological, and biological systems that result from interactions between their components. As data on the intricate relationships within these systems become increasingly available, there is a growing need for more sophisticated models to describe them accurately and offer deeper insights. LÄS MER

  4. 3. Algorithmic discovery, development and personalized selection of higher-order drug cocktails : A label-free live-cell imaging & secretomics approach

    Författare :Efthymia Chantzi; Mats G Gustafsson; Ulf Hammerling; Andreas Bender; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; drug combination discovery and development; personalized pharmacotherapy; higher-order drug combination analysis; quantitative label-free live-cell imaging; secretomics; cell-cell communication; deep learning; convolutional neural networks; data mining; MapReduce; resampling; generalized highest single agent; COMBImageDL; COMBSecretomics; Bioinformatics; Bioinformatik; Pharmacology; Farmakologi; Engineering Science; Teknisk fysik;

    Sammanfattning : An upward trend in clinical pharmacology is the use of multiple drugs to combat complex and co-occurring diseases due to better efficacy, decreased toxicity and reduced risk of evolving resistance. Despite high late-stage attrition rates and the need for multi drug treatments, most drug discovery and development efforts are still mainly focused on new one-size-fits-all monotherapies. LÄS MER

  5. 4. Epigenetic regulation of higher order chromatin conformations and networks

    Författare :Chengxi Shi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Higher order chromatin conformations result from the packaging of the genome into the physical confines of the cell nucleus. Structural hallmarks of the nucleus influence the spatio-temporal behavior of genome underlying the regulation of genomic functions. LÄS MER

  7. 5. Correlations of Higher Order in Networks of Spiking Neurons

    Författare :Stojan Jovanovic; Stefan Rotter; John Hertz; Jeanette Hällgren Kotaleski; Jean-Philippe Bouchard; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Neuronal network; oscillations; correlations; Computer Science; Datalogi;

    Sammanfattning : The topic of this dissertation is the study of the emergence of higher-order correlations in recurrentlyconnected populations of brain cells.Neurons have been experimentally shown to form vast networks in the brain. LÄS MER