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Visar resultat 1 - 5 av 60 avhandlingar som matchar ovanstående sökkriterier.
1. Bipolar electrochemistry for high throughput screening applications
Sammanfattning : Bipolar electrochemistry is an interesting concept for high throughput screening techniques due to the ability to induce gradients in a range of materials and their properties, such as composition, particle size, or dopant levels, among many others. One of the key advantages of the method is the ability to test, create or modify materials without the need for a direct electrical connection. LÄS MER
2. Improved Techniques for High-Throughput Molecular Diagnostics
Sammanfattning : The amount of information derived from sequencing the humangenome is leading to an exponential increase in the rate atwhich genes and genetic disorders are mapped and characterized.As a consequence, the demand for genetic testing is alsodramatically increasing. LÄS MER
3. The p97 ATPase and the Drosophila Proteasome : Protein Unfolding and Regulation
Sammanfattning : For all living systems, there is a requirement to recycle and regulate proteins. In eukaryotic organisms this is accomplished by the proteasome. The p97 ATPase is another highly conserved and essential complex present throughout the eukaryotic cell. LÄS MER
4. Introducing weak affinity chromatography to drug discovery with focus on fragment screening
Sammanfattning : Fragment-based drug discovery is an emerging process that has gained popularity in recent years. The process starts from small molecules called fragments. One major step in fragment-based drug discovery is fragment screening, which is a strategy to screen libraries of small molecules to find hits. LÄS MER
5. Exploring the interplay between mRNA degradation and ribosome dynamics using high-throughput sequencing
Sammanfattning : Regulation of gene expression in response to fluctuating environments is essential for cellular survival. This regulation is multi-faceted, with mRNA abundance determined by both synthesis and decay. mRNA decay regulates transcript abundance, enabling swift transcriptomic adaptations. LÄS MER