Sökning: "high-fat diet"
Visar resultat 11 - 15 av 114 avhandlingar innehållade orden high-fat diet.
11. Modulators of UCP1-dependent thermogenesis : Glucocorticoids, diet and novel research models
Sammanfattning : The activation and recruitment of brown adipose tissue (BAT) thermogenesis has been put forward as a promising strategy to reduce the disease burden of obesity and obesity-related diseases. Heat production by BAT can be attributed to the tissue-specific mitochondrial uncoupling protein 1 (UCP1). LÄS MER
12. Food intake, fibrinolysis and risk factors for cardiovascular disease : studies with special focus on plasminogen activator inhibitor type 1 (PAI-1)
Sammanfattning : Elevated plasminogen activator inhibitor (PAI-1) activity levels, hyperlipemia, hypertension, impaired glucose tolerance and obesity, in particular central obesity, are all related to increased risk for the development of cardiovascular disease.Some risk factors are known to be and shown to be influenced by dietary habits. LÄS MER
13. Prostate cancer : epidemiological studies
Sammanfattning : Prostate cancer is a large and increasing medical problem both in Sweden and in the rest of the developed world, with about 300.000 new cases diagnosed world wide annually. Despite the high incidence of this disease, little is known about the aetiology of prostate cancer. LÄS MER
14. Peripheral apolipoprotein E and its emerging role in neurodegenerative disease
Sammanfattning : The human apolipoprotein E gene (APOE) is polymorphic and coding for three common alleles; ε2, ε3, and ε4. Carriers of the ε4 allele are at a higher risk of developing sporadic late-onset Alzheimer’s Disease (AD). This association appears to be influenced by inherited traits, race, and sex. LÄS MER
15. Perinatal essential fatty acid deficiency in mice: effects on metabolism and behaviour
Sammanfattning : Maternal nutritional status during pregnancy and lactation influences the health of the adult offspring and an adequate supply of essential fatty acids is important for foetal and postnatal growth and development. The overall aim of this thesis was to study short- and long-term effects of perinatal essential fatty acid deficiency in mice on metabolism and behaviour. LÄS MER