Sökning: "high resolution mass spectrometry"

Visar resultat 21 - 25 av 130 avhandlingar innehållade orden high resolution mass spectrometry.

  1. 21. Molecular Tools for Detection and Characterization of Proteins and Extracellular Vesicles in Health and Disease

    Författare :Ehsan Manouchehri Doulabi; Masood Kamali-Moghaddam; Lucia Mincheva-Nilsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; High-resolution mass spectrometry; Proximity ligation assay; Proximity extension assay; Thymidine kinase 1; in situ PLA; High-throughput.; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Detecting molecules involved in cancer is critical for cancer research and diagnostics. To achieve this goal, sensitive protein detection is essential to improving the chances of finding, verifying, validating and developing valuable biomarkers. LÄS MER

  3. 22. Advancing bioinformatics methods for in-depth proteome analysis based on high-resolution mass spectrometry

    Författare :Bo Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mass spectrometry-based shotgun proteomics has become one of the essential techniques for comprehensive studies of living systems. Due to the inherent complexity of proteomes and the data, bioinformatics plays a critical role to translate mass spectra into biological information and knowledge. LÄS MER

  4. 23. Mass spectrometry based analysis of drugs, neurotransmitters and lipids in invertebrate model systems

    Författare :Nhu TN Phan; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CE-MS; Imaging mass spectrometry; Lipids; Neurotransmitters; Drug; Drosophila; C. elegans;

    Sammanfattning : Mass spectrometry (MS) is one of the most universal analytical techniques due to its label-free detection principle and high chemical specificity, high selectivity, and sensitivity. MS is diverse with many different types of systems to meet different analytical demands from various research areas. LÄS MER

  5. 24. Imaging mass spectrometry for in situ lipidomics: from cell structures to cardiac tissue

    Författare :Sanna Sämfors; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Myocardial infarction; PC12 cells; Cell membrane; Mass spectrometry imaging; Sample preparation; Lipidomics; ToF-SIMS; Gas cluster ion beam;

    Sammanfattning : Imaging of cells and tissues is important for studying different processes within biological systems due to the spatial information provided for different molecular species during imaging. One powerful imaging technique is mass spectrometry imaging (MSI). LÄS MER

  7. 25. Surface Modified Capillaries in Capillary Electrophoresis Coupled to Mass Spectrometry : Method Development and Exploration of the Potential of Capillary Electrophoresis as a Proteomic Tool

    Författare :Aida Zuberovic; Jonas Bergquist; Ziad El Rassi; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Topology optimization; Design optimization; Material distribution; Wave propagation problems; Inverse problems; Acoustic devices; Medical microwave tomography; High performance computing; Analytical chemistry; Analytisk kemi;

    Sammanfattning : The increased knowledge about the complexity of the physiological processes increases the demand on the analytical techniques employed to explore them. A comprehensive analysis of the entire sample content is today the most common approach to investigate the molecular interplay behind a physiological deviation. LÄS MER