Sökning: "high pressure polymorphism"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden high pressure polymorphism.

  1. 1. Heritability of blood pressure: monogenes and polygenes

    Författare :Cristiano Fava; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Biomedicinska vetenskaper; Biomedical sciences; kidney; Adducin-1; CLC-kb; Gitelman syndrome; association; heritabilty; genetics; hypertension; Blood pressure; blood pressure variability; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : High blood pressure (BP) is associated with cardiovascular morbidity and mortality. Both genetic and environmental factors are implicated in BP homeostatsis and hypertension development. LÄS MER

  3. 2. Extreme water catalyzed transformations of SiO2, TiO2 and LiAlSiO4

    Författare :Kristina Spektor; Ulrich Häussermann; Gunnar Svensson; Natalia Dubrovinskaia; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; extreme water environments; high pressure polymorphism; hydrous stishovite; titania phase transitions; lithium aluminosilicates; zeolites from glass precursors; hydrous pyroxenes; Materials Chemistry; materialkemi;

    Sammanfattning : The dramatic change in properties of water near its critical point (i.e. T = 374 °C and p = 22.1 MPa, note: 100 MPa = 0. LÄS MER

  4. 3. Avian MHC: variation and selection in the wild

    Författare :Helena Westerdahl; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; polymorphism; balancing selection; cDNA; avian malaria; great reed warbler; Djurekologi; bird; Animal ecology; immune defence; MHC class II; Major Histocompatibility Complex; MHC class I;

    Sammanfattning : In vertebrates the Major Histocompatibility Complex (MHC) plays a central role in the specific immune defence against various pathogens. Compared with other coding genes the MHC genes exhibit an extremely high level of polymorphism that is maintained by balancing selection. LÄS MER

  5. 4. Factors influencing the risk of diabetic nephropathy : analyses of genes, smoking and diet

    Författare :Anna Möllsten; Gisela Dahlquist; Lise Tarnow; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 diabetes; diabetic nephropathy; oxidative stress; smoking; diet; blood pressure; renin-angiotensin system; nitric oxide synthase; Kidney diseases; Njursjukdomar;

    Sammanfattning : Diabetic long-term complications, despite intensive treatment, cause serious handicaps at relatively young age in diabetic patients. Diabetic nephropathy (DN) develops in up to 30% of patients with type 1 diabetes (T1D). LÄS MER

  7. 5. Microarray Technology for Genotyping in Pharmacogenetics

    Författare :Ulrika Liljedahl; Ann-Christine Syvänen; Denis Grant; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; microarray; genotyping; pharmacogenetics; molecular medicine; single nucleotide polymorphism; hypertension; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ;

    Sammanfattning : The studies in this thesis describe the development of a microarray based minisequencing system and its application to highly parallel genotyping of single nucleotide polymorphisms. The technical developments included identification of a three-dimensional microarray surface coating with high binding capacity for oligonucleotides modified with amino groups as the most optimal one for the system. LÄS MER