Visar resultat 1 - 5 av 62 avhandlingar innehållade ordet heterocyclic.
Sammanfattning : Commonly cooked meat dishes contain heterocyclic amines (HAs) at ng/g levels. HAs are animal carcinogens, form DNA adducts in human tissues, and have been associated with increased risk of cancer in epidemiological studies, and it is thus recommended that human intake be decreased. LÄS MER
Sammanfattning : This thesis is divided in four chapters, containing the work realised in two universities and has as the aim the synthesis of nitrogen-containing compounds. The first chapter describes the project realised at The University of Sheffield. LÄS MER
Sammanfattning : Heterocyclic amines formed in meat during cooking are multi-site animal carcinogens and form DNA adducts in human tissues, but their relevance to human carcinogenesis has yet to be determined. The aim of this thesis was to investigate, by epidemiological methods, whether heterocyclic amines are responsible for part of the diet-related cancer burden in humans. LÄS MER
Sammanfattning : The methods that were developed for the synthesis of the heterocyclic natural products luotonin A, ophiuroidine, cephalandole B, and the indol-3-yl-benzoxazinones of cephalandole A are described in this thesis. The reoccurrence of the 4(3H)-quinazolinone structure is a common theme throughout these studies, and an overview of some quinazoline chemistry is introduced in the first chapter. LÄS MER
5. Aerobic Oxidative N-Heterocyclic Carbene Catalysis via Multistep Electron Transfer - Method Development and Applications
Sammanfattning : Oxidation reactions are ubiquitous in synthetic chemistry, but generally suffer from formation of large amounts of potentially toxic byproducts. Aerial oxygen represents an ideal oxidant since it is inexpensive, non-toxic and only forms water as a byproduct. LÄS MER