Sökning: "hereditary breast and ovarian cancer"
Visar resultat 6 - 10 av 23 avhandlingar innehållade orden hereditary breast and ovarian cancer.
6. Molecular Genetic Alterations In Endometrial And Ovarian Cancers
Sammanfattning : Endometrial cancer is the most common gynecological cancer diagnosed in western countries. Complex atypical hyperplasia (CAH) reflects a state of hyperestrinism and its role as a precursor lesion of this cancer is established. LÄS MER
7. Towards improved management of Lynch syndrome; ovarian cancer profiles, risk perception, knowledge and family perspectives
Sammanfattning : Lynch syndrome (hereditary nonpolyposis colorectal cancer) is one of the most common hereditary cancer syndromes and predisposes to several cancer types, including cancer of the colorectum, endometrium and ovaries. Cancer develops at an early age and one third of the individuals are affected by a metachronous cancer. LÄS MER
8. Intrinsic subtypes and prognostic implications in epithelial ovarian cancer
Sammanfattning : Ovarian cancer is the seventh most common cancer in women globally, with approximately 240,000 new cases annually. Although a rare disease, it is the most lethal gynecologic malignancy. Unspecific symptoms result in late diagnosis and a generally poor prognosis. LÄS MER
9. Hereditary Breast Cancer in South Sweden. Early findings from studies on the role of BRCA1
Sammanfattning : The thesis presents the results from investigations into the role of BRCA1 in hereditary cancer in South Sweden. Loss of heterozygosity (LOH) studies found loss of the wildtype allele of BRCA1 to be common in BRCA1 associated breast cancer, but due to the high degree of LOH on chr. LÄS MER
10. Insights into breast cancer: New familial patterns and identification of a potential predictive marker
Sammanfattning : The last proportion of heredity in breast cancer has proven to be somewhat elusive despite massive attempts to identify the associated factors. Approximately 50 percent of breast cancer caused by familial factors is currently explained. LÄS MER