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Visar resultat 1 - 5 av 37 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Clinical Aspects of Hereditary Breast Cancer

   Författare :Niklas Loman; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; Cytologi; onkologi; cancerology; oncology; Cytology; Age of onset; Survival analysis; Incidence; Male breast cancer; Steroid receptors; BRCA2; BRCA1; Breast cancer; hereditary;

   Sammanfattning : A positive family history of breast cancer (BC) is one of the strongest predictors of the disease. Two major BC susceptibility genes, BRCA1 and BRCA2 were identified about a decade ago. In this thesis, studies of different biological. clinical and epidemiological aspects of hereditary BC are presented. LÄS MER

3. 2. Familial and Hereditary Prostate Cancer

   Författare :Ola Bratt; Urologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrology; Urology; screening; risk perception; hereditary; androgen receptor; genetics; Prostate cancer; epidemiology; Urologi; nefrologi;

   Sammanfattning : This thesis is based on research concerning epidemiological, clinical, and psychological aspects of familial and hereditary prostate cancer. Epidemiology: Male first-degree relatives of prostate cancer patients had a three-fold increased prostate cancer risk. LÄS MER

4. 3. Living with deteriorating and hereditary disease : experiences over ten years of persons with muscular dystrophy and their next of kin

   Författare :Katrin Boström; Gerd Ahlström; Berth Danermark; Anders Möller; Örebro universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Social sciences; muscular dystrophy; chronic disease; ten year follow up; next of kin; ICF; activity; sickness impact; hereditary aspects; illness related problems; quality of life; multimethod; content analysis; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; Disability research; Handikappsforskning; Handikappvetenskap; Disability Science;

   Sammanfattning : The overall aim of this thesis was to elucidate haw persona with muscular dystrophy (MD) and their next of kin experience and describe their daily lives over the last ten years. MD is a group of inherited disorders characterised by muscular weakness caused by muscle wasting. Both qualitative and quantitative methods were used. LÄS MER

5. 4. Psychological and Behavioral Aspects of Receiving Genetic Counseling for Hereditary Cancer

   Författare :Afsaneh Hayat Roshanai; Karin Nordin; Richard Rosenquist; Yvonne Brandberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hereditary cancer; genetic counseling; psychological distress; adherence; genetic knowledge; risk perception; sharing genetic information; at-risk relatives’ experiences; informational needs; Clinical genetics; Klinisk genetik; Public health science; Folkhälsovetenskap; Psychology; Psykologi; Genetics; Genetik;

   Sammanfattning : The overall aims of this thesis were to investigate psychological and behavioral effects of receiving cancer genetic counseling for breast, ovarian and colorectal cancer and/or with a family history of these cancer types and to determine whether counselees’ informational needs were met. Study I was performed 3-7 years post-counseling. LÄS MER

7. 5. Hereditary hypercholesterolemia and cardiovascular disease : functional and epidemiological aspects

   Författare :Tigist Wodaje; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background. Individuals with familial hypercholesterolemia (FH) and/or high levels of lipoprotein(a) [Lp(a)] are genetically predisposed to develop early cardiovascular disease (CVD). LÄS MER