Sökning: "hepatocyte growth factor"
Visar resultat 16 - 20 av 27 avhandlingar innehållade orden hepatocyte growth factor.
16. Matrix metalloproteases and cell motility in malignant mesothelioma
Sammanfattning : Invasion and metastasis of malignant tumor cells requires destruction of and migration through extracellular matrix (ECM) such as basement membrane and interstitial stroma. The ECM-degrading proteases produced by tumor cells and stromal cells and cell motility play a crucial role in this process. LÄS MER
17. Exploring functional subsets of cancer-associated fibroblasts
Sammanfattning : The tumor microenvironment consists of several interacting cell types. Cancer research focssed mainly on the malignant cell in the past. The importance of the tumor microenvironment is increasingly appreciated, as endothelial cells and immune cells were identified as targets for anti-tumor therapy. LÄS MER
18. Cell therapy for denervated tissue
Sammanfattning : Background: Peripheral nerve injury results in denervation of tendons and muscles. The biology of denervated muscle has been well studied but little is known about the associated tendons. LÄS MER
19. Hormonal regulation of sex differentiated liver carcinogenesis in the rat
Sammanfattning : Endocrine factors influence cancer development in a variety of reproductive and non-reproductive tissues and organs. The incidence of liver cancer is higher in men than in women and long-term administration of androgens and estrogens has been reported to increase the risk for liver cancer formation, supporting the importance of hormonal factors in the etiology of this tumor. LÄS MER
20. Axl RTK and microRNAs in urogenital cancers
Sammanfattning : This thesis is based on four projects focused on the Axl receptor tyrosine kinase (RTK) and microRNAs in clear cell renal cell carcinoma (ccRCC) and in prostate cancer (PCa). Paper I focuses on differentially expressed microRNAs in ccRCC. LÄS MER