Sökning: "hepatocyte growth factor"

Visar resultat 11 - 15 av 27 avhandlingar innehållade orden hepatocyte growth factor.

  1. 11. Experimental studies on the effects of hepatocyte-based liver support

    Författare :Helene Lilja; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Liver transplantation is limited by lack of donors and consequently there is a need to develop liver support/replacement therapies, such as hepatocyte transplantation (HcTx) and artificial livers. In the present thesis, the effects of these therapies were investigated. First, we established a technique of isolating fetal hepatocytes (FH). LÄS MER

  3. 12. Modulation of mononuclear phagocyte function in the dissemination of Toxoplasma gondii

    Författare :Arne L. ten Hoeve; Antonio Barragan; Nicolas Blanchard; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apicomplexa; dendritic cell; macrophage; intracellular signaling; parasite-derived effector protein; chemotaxis; leukocyte migration; transcription factor; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Toxoplasma gondii is an obligate intracellular Apicomplexan parasite that could possibly infect all warm-blooded animals. Acute infections with T. LÄS MER

  4. 13. Satellite cells in human skeletal muscle : molecular identification quantification and function

    Författare :Mona Lindström; Lars-Eric Thornell; Hannu Kalimo; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; satellite cell markers; NCAM; Pax7; MyoD; myogenin; DLK1 FA1; c-Met; human skeletal muscle; immunohistochemistry; muscle growth; muscle hypertrophy; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; anatomi; Human Anatomy;

    Sammanfattning : Skeletal muscle satellite cells located between the plasma membrane and the basal lamina of muscle fibres, could for many years, only be studied in situ by electron microscopy. The introduction of immunohistochemistry and the discovery of molecular markers of satellite cells then made them accessible for light microscopic studies and a wealth of information is today available. LÄS MER

  5. 14. Studies on growth hormone regulation of the CYP2C12 gene in rat liver

    Författare :Hanna Helander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Growth hormone (GH) is secreted from the pituitary gland in a sexually dimorphic manner in the rat. This leads to a sexual dimorphism in the expression of a number of hepatic GH-target genes including members of the cytochrome P450 (CYP) family. LÄS MER

  7. 15. Cryo-electron tomography of individual protein molecules

    Författare :Sara Sandin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cryo-Electron Microscopy; Cryo-Electron Tomography; Protein Conformation; Antibodies; Immunoglobulin G; Glucocorticoid Receptor; Hepatocyte Growth Factor Scatter Factor; Receptor Tyrosine Kinase MET;

    Sammanfattning : Averaging methods of determining structure, such as X-ray diffraction, do not preserve information about the flexibility of molecules. Cryo-electron tomography allows us to reconstruct individual hydrated objects. LÄS MER