Sökning: "hepatic steatosis"
Visar resultat 6 - 10 av 31 avhandlingar innehållade orden hepatic steatosis.
6. Modelling of steatosis and insulin resistance development in human hepatic 3d spheroids : mechanisms and genetic aspects
Sammanfattning : Hepatic steatosis and insulin resistance are common disease manifestations seen in metabolic syndrome, non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D) patients. Aberrant hepatic lipid accumulation leads to both morphological changes and metabolic alterations in liver function and may cause serious end-stage liver disease. LÄS MER
7. The Non-Invasive Liver Biopsy : Determining Hepatic Function in Diffuse and Focal LiverDisease
Sammanfattning : The liver is one of the largest organs within the human body and it handles many vital tasks such as nutrient processing, toxin removal, and synthesis of important proteins. The number of people suffering from chronic liver disease is on the rise, likely due to the present ‘western’ lifestyle. LÄS MER
8. Adipose tissue inflammation, hepatic fat accumulation and insulin resistance
Sammanfattning : Insulin resistance is the central feature of a variety of metabolic disorders, such as type 2 diabetes and the metabolic syndrome. The incidence of these disorders, often together with obesity, is currently increasing throughout the world. LÄS MER
9. On the role of gut microbiota in intestinal physiology and hepatic metabolism
Sammanfattning : The gut microbiota, a complex and dynamic community of microbes in the mammalian gut, has coevolved with us for ample time providing mutual benefits. However, mechanistic knowledge of these has been limited, but are now becoming increasingly clear. LÄS MER
10. Importance of iron overload and steatosis in patients with chronic liver disease
Sammanfattning : This thesis deals with the importance of hepatic iron and fat deposition in the context of chronicliver disease, with special focus on the role of the S65C mutation in the hemochromatosis cryptogenic cirrhosis (CC) in patients evaluated for liver transplantation, the expressions of innate and adaptive immunity in non-alcoholic steatohepatitis (NASH), and the role of the ironregulatory hormone hepcidin in dysmetabolic iron overload (DIO). NAFLD is the most common liver disease in the Western world. LÄS MER