Sökning: "hepatic steatosis"

Visar resultat 16 - 20 av 31 avhandlingar innehållade orden hepatic steatosis.

  1. 16. Translational genetics identifies a novel target to treat fatty liver disease

    Författare :Kavitha Sasidharan; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fatty liver disease; human genetics; GWAS; PSD3; spheroids;

    Sammanfattning : Fatty liver disease (FLD) is rapidly prevailing as the most common liver disease worldwide, with an estimated of one-quarter of the global population affected. Environmental and genetic determinants contribute to FLD susceptibility. LÄS MER

  3. 17. The mechanism of action of SOCS2 and its role in metabolism and growth

    Författare :Mattias Vesterlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A well-known function of Growth Hormone (GH) is the regulation of postnatal longitudinal growth but it also affects other biological processes, for instance metabolism and inflammation. Actions of GH are tightly regulated at several levels and by several different factors and are initiated by GH binding to membrane bound GH receptors (GHR). LÄS MER

  4. 18. The role of MBOAT7 on fatty liver disease

    Författare :Andrea Caddeo; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver disease; medicine; Genetics; NAFLD;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) is the main health disorder in internal medicine, affecting one third of the population worldwide. Environmental and genetic factors contribute to NAFLD susceptibility and progression. LÄS MER

  5. 19. Understanding the genetic architecture of fatty liver disease

    Författare :Jamialahmadi Oveis; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-alcoholic fatty liver disease; Polygenic risk score; Genomewide association studies; Mendelian Randomization;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease, ranging from simple steatosis to more severe conditions, namely non-alcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). NAFLD has a strong genetic component, and its heritability depends on environmental factors and ethnicity. LÄS MER

  7. 20. Aspects of diagnosis, prognosis and treatment of nonalcoholic fatty liver disease

    Författare :Magnus Holmer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally. NAFLD is caused by obesity, often in combination with type 2 diabetes mellitus (T2D). Lifestyle modifications that lead to weight loss, primarily diet change, is the only treatment proven to reverse steatosis and nonalcoholic steatohepatitis (NASH). LÄS MER