Sökning: "hepatic steatosis"

Visar resultat 11 - 15 av 31 avhandlingar innehållade orden hepatic steatosis.

  1. 11. Epidemiology and clinical importance of GB virus C/hepatitis G virus

    Författare :Robert Halasz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :GBV-C; HGV; prevalence; transmission; children; fulminant hepatic failure; clinical importance;

    Sammanfattning : GB virus C (GBV-C) or hepatitis G virus (HGV) is a recently discovered enveloped RNA virus belonging to the Flaviviridae family. GBV-C/HGV has been suggested to be a causative agent of non-A-non-E hepatitis. However, several contradictory observations cast doubts that it actually causes hepatitis. LÄS MER

  3. 12. MST3 and MST4: Critical Regulators of Liver Lipid Partitioning and Hepatocarcinogenesis

    Författare :Mara Caputo; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-alcoholic fatty liver disease; non-alcoholic steatohepatitis; hepatocellular carcinoma; STE20-type kinases; MST3; MST4; lipid droplets; antisense oligonucleotide treatment; fibrosis;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) encompasses a disease spectrum ranging from hepatic steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, and finally cirrhosis. With no approved pharmacological treatment, NAFLD is currently the most common etiology of chronic liver disease in Western countries and its prevalence continues to grow. LÄS MER

  4. 13. Fighting cardiometabolic disease : validation of new experimental models and therapeutic targets

    Författare :Mirko Enea Minniti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prevalence of cardiometabolic diseases (CMD) such as atherosclerotic cardiovascular diseases, type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), has grown dramatically during the last decades. Hence, massive research efforts are allocated to identify the pathophysiological mechanisms and new therapeutic targets for these morbidities. LÄS MER

  5. 14. Non-Alcoholic Fatty Liver Disease : Aspects on Diagnosis and Long-term Prognosis

    Författare :Patrik Nasr; Stergios Kechagias; Mattias Ekstedt; Peter Lundberg; Einar Stefán Björnsson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease affecting approximately 25% of the global population and is commonly recognized as the hepatic manifestation of the metabolic syndrome. The histological spectrum of NAFLD ranges from isolated steatosis to non-alcoholic steatohepatitis (NASH), with risk of developing fibrosis and subsequent cirrhosis and hepatocellular carcinoma. LÄS MER

  7. 15. Non-alcoholic fatty liver disease : an emerging liver disease

    Författare :Cecilia Söderberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of the study was to evaluate what NAFLD is from a molecular perspective, what influences the disease progression and what the prognosis of the disease is. Fatty liver has earlier often been associated with excessive alcohol intake and only in the last two decades has it been viewed as a condition in non- drinkers i.e. LÄS MER