Sökning: "hemostasis"

Visar resultat 11 - 15 av 57 avhandlingar innehållade ordet hemostasis.

  1. 11. The effect of sex hormones on hemostasis and cardiovascular riskfactors in postmenopausal women

    Författare :Ulla Pripp; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Postmenopausal women; cardiovascular risk factors; hemostasis; ambulatory blood pressure; angina pectoris; HRT;

    Sammanfattning : The influence of cardiac riskfactors and sex hormones on hemostasis were studied in healthy women (n=260) in Study I. Body mass Index (BMI), dyslipidemia, surgical menopause, smoking and years since menopause were associated with an increase of 28% in fibrinogen levels. BMI, total cholesterol (tot. chol. LÄS MER

  3. 12. Effects of nitric oxide on hemostasis with special attention to platelet function

    Författare :Johanna Albert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :nitric oxide; bleeding time; platelet aggregation; platelet secretion; P-selectin expression; flow cytometry; NG-monomethyl-L-arginine; L-NMMA; nasal air; skin perfusion; GSNO; humans;

    Sammanfattning : Endogenous endothelium-derived NO provides a continuous vasodilating effect, but may also in humans have an antithrombotic effect, which is exerted by inhibition of platelet function and by vasodilatation. Inhalation of NO selectively relaxes the pulmonary vascular bed, without causing systemic hypotension. LÄS MER

  4. 13. Microparticles in hemophilia : friend or foe? To improve hemostasis or to induce atherothrombosis?

    Författare :Yanan Zong; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : As one of the most well-known inherited bleeding disorders, hemophilia A (HA) is caused by the deficiency or dysfunction of coagulation factor VIII (FVIII). Patients with HA (PWHA) suffer from abnormal bleeding after injuries or surgeries, or even spontaneous bleeding in severe cases, particularly at joints and muscles. LÄS MER

  5. 14. Effects of direct oral anticoagulant treatment on hemostasis in patients with atrial fibrillation

    Författare :Viktor Schutz Taune; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The direct oral anticoagulants (DOAC) – dabigatran, rivaroxaban, apixaban and edoxaban – were approved without the need for routine monitoring. However, in parallel with clinical implementation, studies on how to measure the effect of DOACs have become a research area of increasing interest during the last decade. LÄS MER

  7. 15. Bleeding and hemostasis during normo- and hypothermia : studies on porcine and rat models

    Författare :Göran Heinius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Numerous animal studies have shown protective effects of hypothermia (HT) on hemorrhagic shock. These findings do not correlate with clinical findings, were studies on trauma registers have shown that HT is an independent factor of death when associated with trauma. LÄS MER