Sökning: "hemolytic activity"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden hemolytic activity.

  1. 1. Studies of the pathogenesis of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura

    Författare :Diana Karpman; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatri; Pediatrics; tumor necrosis factor; interleukin 6; von Willebrand factor; apoptosis; lipopolysaccharide; shiga-like toxin; Escherichia coli O157:H7; Hemolytic uremic syndrome; thrombotic thrombocytopenic purpura; Urology; nephrology; Urologi; nefrologi;

    Sammanfattning : This study investigated the pathogenesis of hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). (1) The relative roles of lipopolysaccharide and Shiga-like toxin-2 were studied in a mouse model of Escherichia coli O157:H7 infection. LÄS MER

  3. 2. Studies of EHEC and the complement system in renal diseases

    Författare :Zivile Békassy; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EHEC; hemolytic uremic syndrome; thrombotic microangiopathy; atypical hemolytic uremic syndrome; alternative pathway of complement; dense deposit disease; eculizumab;

    Sammanfattning : This thesis addressed the diagnosis, pathogenesis and clinical course of specific renal diseases hemolytic uremic syndrome (HUS) and dense deposit disease (DDD). HUS may be associated with infection caused by Enterohemorrhagic Escherichia coli (EHEC) or with complement dysfunction due to complement mutations or auto-antibodies (atypical HUS, aHUS). LÄS MER

  4. 3. Genetic, molecular and functional analyses of factor I - an inhibitor of the complement system

    Författare :Sara Nilsson; Malmö Proteinkemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atypical hemolytic uremic syndrome; deficiency; Complement inhibition; factor I; renal disease;

    Sammanfattning : Factor I (FI) is a serine protease that inhibits the complement system by cleaving activated C3 and C4 complement proteins, in the presence of cofactors. Mutations in the gene coding for FI have been identified in complete FI deficient- and atypical hemolytic uremic syndrome (aHUS) patients. LÄS MER

  5. 4. Bio-based nonionic antimicrobial polymers with isatin or indole functionality

    Författare :Xiaoya Li; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antimicrobial polymers; nonionic; isatin; indole; miscibility; hemolytic activity; cytotoxicity;

    Sammanfattning : Infections by pathogenic microorganisms remain one of the most serious concerns in several areas, particularly in hygienic applications. Antimicrobials have been used to combat these infections. Using small molecular antimicrobials as additives or coatings is an industrially adopted strategy. LÄS MER

  7. 5. Extracellular vesicles in Shiga toxin-mediated disease

    Författare :Annie Willysson; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular vesicles; Shiga toxin; EHEC; hemolytic uremic syndrome;

    Sammanfattning : Extracellular vesicles are released during infectious, inflammatory and prothrombotic conditions. These are membrane-derived vesicles shed by cells during activation, senescence and/or apoptosis. Extracellular vesicles contain and transfer components of the parent cell from which they are shed. LÄS MER