Sökning: "hemoglobin"

Visar resultat 11 - 15 av 222 avhandlingar innehållade ordet hemoglobin.

  1. 11. An Investigation of Peroxidase Activity in Biomimetic and Biological Systems

    Författare :Ekaterina Ryabova; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; metabolism; Metabolism; enzymologi; Proteiner; enzymology; Proteins; hemoglobin; catalysis; peptide; peroxidase; protoporphyrin IX; Biokemi; Biochemistry;

    Sammanfattning : In order to create a heme environment which permits biomimicry of heme-containing plant peroxidases and investigate the role played by the vinyl side chains of the porphyrin ring on the stability and, possibly, catalytic activity of model compounds, a number of new synthetic microperoxidases -– hemin-6(7)-gly-his methyl ester (HGH) and hemin-6(7)-gly-gly-his methyl ester (HGGH) and hemin-6,7-bis(gly-gly-his methyl ester) (H2GGH) as well as mesohemin-6(7)-gly-gly-his methyl ester (MGGH) and deuterohemin-6(7)-gly-gly-his methyl ester (DGGH) have been prepared by condensation of a peptide residue with the propionic side chains of hemin, mesohemin and deuterohemin, respectively. Reactivity studies towards different organic and inorganic substrates showed that not only five- but also six-coordinate hemin peptide complexes catalyze the oxidation of substrates by H2O2. LÄS MER

  2. 12. Multimodal Interaction Chromatography for the Investigation and Separation of Proteins

    Författare :Kristian Kallberg; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hydrophobic interaction chromatography; Multimodal chromatography; Glycosylation; Antibody; Hemoglobin; Protein purification.;

    Sammanfattning : Minor structural changes on the surface of proteins can have tremendous impact on their biological properties. When producing therapeutic proteins it is therefore important to verify that the generated protein is the desired one. LÄS MER

  3. 13. Disordered matter: From Ionic Glasses to Proteins

    Författare :Charbel Tengroth; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; liquid-glass transition; PPG; disorder; B2O3; neutron scattering; hemoglobin; time-resolved resonance Raman scattering; CKN;

    Sammanfattning : Understanding the glassy state is regarded as one of the ten most important questions in physics in the 21st century [1]. This thesis deals with structure and dynamics of a few model disordered systems ranging from an ionic glass to proteins. The structure of an ionic liquid, Ca0.4K0. LÄS MER

  4. 14. Protein adducts of hexahydrophthalic anhydride- chemical structures and biomarkers

    Författare :Monica Kåredal; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; arbetsmiljömedicin; Yrkesmedicin; industrial medicine; Occupational health; nasal lavage; mass spectrometry; biomarker; human serum albumin; hemoglobin; Hexahydrophthalic anhydride; adducts;

    Sammanfattning : Organic acid anhydrides (OAAs) are low molecular weight chemicals used in the industry for manufacturing of plastics such as epoxy resins. Exposure to these chemicals may lead to symptoms from the eyes and the respiratory tract in form of conjunctivitis, rhinitis and asthma. LÄS MER

  5. 15. Initiation of spleen contraction resulting in natural blood boosting in humans

    Författare :Angelica Lodin; Erika Schagatay; Mats H. Linér; Mittuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acclimatization; altitude; apnea; breath-hold diving; hemoglobin; hypercapnia; hypoxia; triggers;

    Sammanfattning : The spleen has been shown to contract in apneic situations in humans as well as in other diving mammals, expelling its stored red blood cell content into circulation. This natural blood boosting may increase the circulating hemoglobin concentration (Hb) by up to 10%, which would enhance the oxygen carrying capacity and likely increase performance. LÄS MER